DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment psh and masp2

DIOPT Version :9

Sequence 1:	NP_573297.1	Gene:	psh / 32832	FlyBaseID:	FBgn0030926	Length:	394	Species:	Drosophila melanogaster
Sequence 2:	NP_001011037.1	Gene:	masp2 / 496446	XenbaseID:	XB-GENE-1007491	Length:	687	Species:	Xenopus tropicalis

Alignment Length:	407	Identity:	108/407 - (26%)
Similarity:	166/407 - (40%)	Gaps:	104/407 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 WSLLLGTFVLISCSSVE-------AAVTVGRACKVTDTMPGICRTSSDCEPLIDGYIKSGVLTLN 62
            |...|...::::|.:.:       :.||..........:...|     .||.   |||.|    .
Frog   353 WDKKLPKCIIVNCGNPDDIENGTYSFVTAKEVTLYNSVVQYNC-----TEPY---YIKEG----K 405

  Fly    63 DVPSCGL-GAWGEIFC-CPTKPCCDNSTITSVSTSSTTSTKAPMTSGRVDVPTFGSGDRPAVAAC 125
            ....||. |.|.:|.. ..|.|.|                          ||..|
Frog   406 GEYRCGADGFWEDIESEKKTPPIC--------------------------VPDCG---------- 434

  Fly   126 KKIRERKQQRSGNQLVIHIVGGYPVDPGVYPHMAAIGYITFGTDFRCGGSLIASRFVLTAAHCV- 189
                :||...:|     .||||...:.|.:|....|.    ..:.|.||:|:...::|||||.|
Frog   435 ----KRKPAAAG-----RIVGGEFANVGEFPWQVFIN----ANNERGGGALLLDNWILTAAHVVY 486

  Fly   190 NTDANTPAFVRLGAVNIENPDHSYQDIVIR----SVKIHPQYVGNKY-NDIAILELERDV-VETD 248
            :.|..:...:::|.::.:  |.:|    ||    :|.||..|....| ||||:::|:..| :..:
Frog   487 SYDDLSSILIKMGFLSTQ--DSNY----IRGWPEAVFIHEGYKPGHYNNDIALIKLKNKVPLSEE 545

  Fly   249 NIRPACL-------HTDATDPPSNSKFFVAGWGVLNVTTRARSKILLR-AGLELVPLDQCNISYA 305
            :|...||       |....| ..|....|||||   :|...||...|| ..:.:|....|...||
Frog   546 SILGICLPTKEKSYHISHKD-DDNHVGLVAGWG---LTEAQRSSRKLRFVEVNIVDHSTCKAEYA 606

  Fly   306 EQPGSIRLLKQGVI-DSLLCAIDQKLIADACKGDSGGPLIHELNVEDGMYTIMGVISSGFGCATV 369
                  :|..|.:: ::::||..:..:.|:|.|||||.|.. :|.|...:.:.|::|.|.||...
Frog   607 ------KLDAQYIVTENMICAGFEIGVKDSCAGDSGGALAF-MNAESKKWFVGGIVSWGVGCGVA 664

  Fly   370 TP-GLYTRVSSYLDFIE 385
            .. |:||:|::|||:||
Frog   665 RQYGVYTKVTNYLDWIE 681

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
psh	NP_573297.1	CLIP	30..79	CDD:197829	12/50 (24%)
		Tryp_SPc	143..384	CDD:214473	80/257 (31%)
		Tryp_SPc	144..387	CDD:238113	82/259 (32%)
masp2	NP_001011037.1	CUB	30..139	CDD:238001
		FXa_inhibition	145..180	CDD:317114
		CUB	184..294	CDD:238001
		CCP	299..361	CDD:153056	2/7 (29%)
		CCP	365..430	CDD:153056	18/102 (18%)
		Tryp_SPc	443..680	CDD:214473	80/257 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910