DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment psh and GZMA

DIOPT Version :9

Sequence 1:	NP_573297.1	Gene:	psh / 32832	FlyBaseID:	FBgn0030926	Length:	394	Species:	Drosophila melanogaster
Sequence 2:	NP_006135.2	Gene:	GZMA / 3001	HGNCID:	4708	Length:	262	Species:	Homo sapiens

Alignment Length:	268	Identity:	73/268 - (27%)
Similarity:	115/268 - (42%)	Gaps:	69/268 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   144 IVGGYPVDPGVYPHMAAIGYITFGTDFR--CGGSLIASRFVLTAAHCVNTDANTPAFVRLGAVNI 206
            |:||..|.|...|:|     :....|.:  |.|:|||..:|||||||   :.|..:.|.|||.:|
Human    29 IIGGNEVTPHSRPYM-----VLLSLDRKTICAGALIAKDWVLTAAHC---NLNKRSQVILGAHSI 85

  Fly   207 ENPDHSYQDIVIRSVKIHPQYVG------------------NKYNDIAILELERDVVETDNIRPA 253
            ...:.:.|.::::....:|.|..                  |||  :.||.|.:   :.|:::|.
Human    86 TREEPTKQIMLVKKEFPYPCYDPATREGDLKLLQLMEKAKINKY--VTILHLPK---KGDDVKPG 145

  Fly   254 CLHTDATDPPSNSKFFVAGWGVLNVTTRARSKILLRAGLELVPLDQCN--ISYAEQPGSIRLLKQ 316
            .:..            |||||..: .:.:.|..|....:.::....||  ..|...|
Human   146 TMCQ------------VAGWGRTH-NSASWSDTLREVNITIIDRKVCNDRNHYNFNP-------- 189

  Fly   317 GVID-SLLCAIDQKLIADACKGDSGGPLIHELNVEDGMYTIMGVISSGF--GCATVT-PGLYTRV 377
             ||. :::||...:...|:|.||||.||:.|     |::  .||.|.|.  .|.... ||:|..:
Human   190 -VIGMNMVCAGSLRGGRDSCNGDSGSPLLCE-----GVF--RGVTSFGLENKCGDPRGPGVYILL 246

  Fly   378 S-SYLDFI 384
            | .:|::|
Human   247 SKKHLNWI 254

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
psh	NP_573297.1	CLIP	30..79	CDD:197829
		Tryp_SPc	143..384	CDD:214473	72/266 (27%)
		Tryp_SPc	144..387	CDD:238113	73/268 (27%)
GZMA	NP_006135.2	Tryp_SPc	29..254	CDD:238113	72/266 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D476534at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	1.010