DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment psh and Gzmk

DIOPT Version :9

Sequence 1:	NP_573297.1	Gene:	psh / 32832	FlyBaseID:	FBgn0030926	Length:	394	Species:	Drosophila melanogaster
Sequence 2:	NP_032222.1	Gene:	Gzmk / 14945	MGIID:	1298232	Length:	263	Species:	Mus musculus

Alignment Length:	254	Identity:	73/254 - (28%)
Similarity:	117/254 - (46%)	Gaps:	27/254 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly   144 IVGGYPVDPGVYPHMAAIGYITFGTDFRCGGSLIASRFVLTAAHCVN--TDANTPAFVRLGAVNI 206
            |:||..|.|...|.||:|.|   .:...|||.||..::|||||||.:  ...::|..| |||.::
Mouse    26 IIGGREVQPHSRPFMASIQY---RSKHICGGVLIHPQWVLTAAHCYSWFPRGHSPTVV-LGAHSL 86

  Fly   207 ENPDHSYQDIVIRS-VKIHPQYVGNKYNDIAILELERDVVETDNIRPACLHTDATD-PPSNSKFF 269
            ...:...|...|:. :.......|:..:||.:::|........|::  .||..:.: ....:|..
Mouse    87 SKNEPMKQTFEIKKFIPFSRLQSGSASHDIMLIKLRTAAELNKNVQ--LLHLGSKNYLRDGTKCQ 149

  Fly   270 VAGWGVLNVTTRARSKILLRAGLELVPLDQCNI-SYAEQPGSIRLLKQGVIDSLLCAIDQKLIAD 333
            |.|||.........|..|....:.::...:||. ||...       |..:...::||.|.:...|
Mouse   150 VTGWGTTKPDLLTASDTLREVTVTIISRKRCNSQSYYNH-------KPVITKDMICAGDARGQKD 207

  Fly   334 ACKGDSGGPLIHELNVEDGMYTIMGVISSGFGCATV-TPGLYTRVS-SYLDFIEGIVWP 390
            :||||||||||.:     |::  ..::|.|:.|... .||:||.:: .|..:|:..:.|
Mouse   208 SCKGDSGGPLICK-----GIF--HALVSQGYKCGIAKKPGIYTLLTKKYQTWIKSKLAP 259

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
psh	NP_573297.1	CLIP	30..79	CDD:197829
		Tryp_SPc	143..384	CDD:214473	71/246 (29%)
		Tryp_SPc	144..387	CDD:238113	72/249 (29%)
Gzmk	NP_032222.1	Tryp_SPc	25..253	CDD:214473	71/246 (29%)
Gzmk	NP_032222.1	Tryp_SPc	26..256	CDD:238113	72/249 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D476534at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010