DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Hayan and Prss22

DIOPT Version :9

Sequence 1:	NP_001097020.1	Gene:	Hayan / 32831	FlyBaseID:	FBgn0030925	Length:	637	Species:	Drosophila melanogaster
Sequence 2:	XP_006524968.4	Gene:	Prss22 / 70835	MGIID:	1918085	Length:	365	Species:	Mus musculus

Alignment Length:	351	Identity:	98/351 - (27%)
Similarity:	156/351 - (44%)	Gaps:	52/351 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly   306 EPYRFRGQDRDKDTQPQEPWNDVSNNLDADPAPSIFNPAETRPTTP--------NPNPS------ 356
            |||..           |.|...||:|    .|...|.||.:...:|        .|.|:
Mouse    24 EPYTL-----------QPPVLPVSSN----TALRSFEPASSLAGSPPIPAMMISRPPPALGGDQF 73

  Fly   357 ----RVNLPEKERPSVAACEKIRSG-GKPLTVH-ILDGERVDRGVYPHMAAIAYNSFGSAAFRCG 415
                .:.|.....|..||..::... |||..:: |:.||......:|.:.:|..|    .:..|.
Mouse    74 SILILLVLLTSTAPISAATIRVSPDCGKPQQLNRIVGGEDSMDAQWPWIVSILKN----GSHHCA 134

  Fly   416 GSLIASRFVLTAAHCVNSDDSTPSF--VRLGALNIENPEPGYQDINVIDVQIHPDYS-GSSKYYD 477
            |||:.:|:|:|||||..|:...||.  |.|||..:.:|.|..|.:.:..|..||.|| ....:.|
Mouse   135 GSLLTNRWVVTAAHCFKSNMDKPSLFSVLLGAWKLGSPGPRSQKVGIAWVLPHPRYSWKEGTHAD 199

  Fly   478 IAILQLAEDAKESDVIRPACLYTDRSDPPANYKYFVAGWG-VMNVTNRAVSKILLRAALDLVPAD 541
            ||:::|....:.|:.|.|.||.......|.....::|||| :.:.......:.|.:..:.::.::
Mouse   200 IALVRLEHSIQFSERILPICLPDSSVRLPPKTDCWIAGWGSIQDGVPLPHPQTLQKLKVPIIDSE 264

  Fly   542 ECNASFAEQPSANRTLRRGVIASQLCAADKNQRKDACQGDSGGPLILEIDDVDGTYSIVGVISSG 606
            .|.:.:.....     :..:....|||......:|||.|||||||:.::||   .:.:.|:||.|
Mouse   265 LCKSLYWRGAG-----QEAITEGMLCAGYLEGERDACLGDSGGPLMCQVDD---HWLLTGIISWG 321

  Fly   607 FGCATKT-PGLYTRVSSFLDYIEGIV 631
            .|||.:. ||:||.:.:...:::.||
Mouse   322 EGCAERNRPGVYTSLLAHRSWVQRIV 347

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Hayan	NP_001097020.1	CLIP	32..80	CDD:197829
		Tryp_SPc	384..627	CDD:214473	74/248 (30%)
		Tryp_SPc	385..630	CDD:238113	74/249 (30%)
Prss22	XP_006524968.4	Tryp_SPc	108..346	CDD:238113	74/249 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910