Protein Alignment Hayan and PRSS22

DIOPT Version :10

• Sequence 1: NP_001097020.1
• Gene: Hayan / 32831
• FlyBaseID: FBgn0030925
• Length: 637
• Species: Drosophila melanogaster
• Sequence 2: XP_054169579.1
• Gene: PRSS22 / 64063
• HGNCID: 14368
• Length: 425
• Species: Homo sapiens
• Alignment Length: 302
• Identity: 91/302 - (30%)
• Similarity: 144/302 - (47%)
• Gaps: 41/302 - (13%)

  Fly   343 PAETRPTTPNP----NPSRVNLPEKERPSVAACEKIRSGGKPLTVH-ILDGERVDRGVYPHMAAI 402
            |...|....:|    |.:|:.:|       .||      |||..:: ::.||......:|.:.:|
Human   124 PGHWRARGSSPPAILNAARIPVP-------PAC------GKPQQLNRVVGGEDSTDSEWPWIVSI 175

  Fly   403 AYNSFGSAAFRCGGSLIASRFVLTAAHCVNSDDSTPSF--VRLGALNIENPEPGYQDINVIDVQI 465
            ..|    ....|.|||:.||:|:|||||...:.:.|..  |.|||..:.||....|.:.|..|:.
Human   176 QKN----GTHHCAGSLLTSRWVITAAHCFKDNLNKPYLFSVLLGAWQLGNPGSRSQKVGVAWVEP 236

  Fly   466 HPDYS---GSSKYYDIAILQLAEDAKESDVIRPACLYTDRSDPPANYKYFVAGWG-VMNVTNRAV 526
            ||.||   |:..  |||:::|....:.|:.:.|.||.......|.|...:::||| :.:......
Human   237 HPVYSWKEGACA--DIALVRLERSIQFSERVLPICLPDASIHLPPNTHCWISGWGSIQDGVPLPH 299

  Fly   527 SKILLRAALDLVPADECNASFAEQPSANRTLRRGVIA-SQLCAADKNQRKDACQGDSGGPLILEI 590
            .:.|.:..:.::.::.|:..:.      |...:|.|. ..|||......:|||.|||||||:.:
Human   300 PQTLQKLKVPIIDSEVCSHLYW------RGAGQGPITEDMLCAGYLEGERDACLGDSGGPLMCQ- 357

  Fly   591 DDVDGTYSIVGVISSGFGCATKT-PGLYTRVSSFLDYIEGIV 631
              |||.:.:.|:||.|.|||.:. ||:|..:|:...::|.||
Human   358 --VDGAWLLAGIISWGEGCAERNRPGVYISLSAHRSWVEKIV 397

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hayan	NP_001097020.1	CLIP	32..80	CDD:197829
		Tryp_SPc	385..630	CDD:238113	78/252 (31%)
PRSS22	XP_054169579.1	Tryp_SPc	158..396	CDD:238113	78/252 (31%)