Protein Alignment Hayan and KLK1

DIOPT Version :10

• Sequence 1: NP_001097020.1
• Gene: Hayan / 32831
• FlyBaseID: FBgn0030925
• Length: 637
• Species: Drosophila melanogaster
• Sequence 2: NP_002248.1
• Gene: KLK1 / 3816
• HGNCID: 6357
• Length: 262
• Species: Homo sapiens
• Alignment Length: 284
• Identity: 79/284 - (27%)
• Similarity: 127/284 - (44%)
• Gaps: 55/284 - (19%)

  Fly   371 CEKIRSGG----KPLTVHILDGERVDRGVYPHMAAIAYNSFGSAAFRCGGSLIASRFVLTAAHCV 431
            |..:..||    .|:...|:.|...::...|..||:.:.|    .|:|||.|:..::|||||||:
Human     7 CLALSLGGTGAAPPIQSRIVGGWECEQHSQPWQAALYHFS----TFQCGGILVHRQWVLTAAHCI 67

  Fly   432 N-------------SDDSTPSFVRLGALNIENPEPGYQDINVID---VQIHPDYSGSSKYYDIAI 480
            :             .|::|..||.:..   ..|.||: ::::::   .|...|||     :|:.:
Human    68 SDNYQLWLGRHNLFDDENTAQFVHVSE---SFPHPGF-NMSLLENHTRQADEDYS-----HDLML 123

  Fly   481 LQLAEDAKE-SDVIRPACLYTDRSDPPANYKYFVAGWGVMNVTNRAVSKILLRAALDLVPADECN 544
            |:|.|.|.. :|.::...|.|:  :|........:|||.:...|.:....|....|.::|.|||.
Human   124 LRLTEPADTITDAVKVVELPTE--EPEVGSTCLASGWGSIEPENFSFPDDLQCVDLKILPNDECK 186

  Fly   545 ASFAEQPSANRTLRRGVIASQLCAADKNQRKDACQGDSGGPLILEIDDVDGTYSIVGVISSGF-G 608
            .:..::          |....||.......||.|.|||||||:     .||.  :.||.|.|: .
Human   187 KAHVQK----------VTDFMLCVGHLEGGKDTCVGDSGGPLM-----CDGV--LQGVTSWGYVP 234

  Fly   609 CAT-KTPGLYTRVSSFLDYIEGIV 631
            |.| ..|.:..||.|::.:||..:
Human   235 CGTPNKPSVAVRVLSYVKWIEDTI 258

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hayan	NP_001097020.1	CLIP	32..80	CDD:197829
		Tryp_SPc	385..630	CDD:238113	75/263 (29%)
KLK1	NP_002248.1	Tryp_SPc	25..257	CDD:238113	75/263 (29%)