Protein Alignment Hayan and HGFAC

DIOPT Version :10

• Sequence 1: NP_001097020.1
• Gene: Hayan / 32831
• FlyBaseID: FBgn0030925
• Length: 637
• Species: Drosophila melanogaster
• Sequence 2: NP_001284368.1
• Gene: HGFAC / 3083
• HGNCID: 4894
• Length: 662
• Species: Homo sapiens
• Alignment Length: 298
• Identity: 89/298 - (29%)
• Similarity: 129/298 - (43%)
• Gaps: 51/298 - (17%)

  Fly   360 LPEKERPSVAACEKIRSGGKPLTVHILDGERVDRGVYPHMAAIAY-NSFGSAAFRCGGSLIASRF 423
            |||...|...||.:.......|...|:.|.....|.:|.:|||.. :||      |.|||:.:.:
Human   390 LPEPASPGRQACGRRHKKRTFLRPRIIGGSSSLPGSHPWLAAIYIGDSF------CAGSLVHTCW 448

  Fly   424 VLTAAHCVNSDDSTPSF-VRLG------------ALNIEN--PEPGYQDINVIDVQIHPDYSGSS 473
            |::||||.:......|. |.||            ...||.  |...|...|..|
Human   449 VVSAAHCFSHSPPRDSVSVVLGQHFFNRTTDVTQTFGIEKYIPYTLYSVFNPSD----------- 502

  Fly   474 KYYDIAILQLAED----AKESDVIRPACLYTDRSDPPANYKYFVAGWGVMNVTNRAVSKILLRAA 534
              :|:.:::|.:.    |..|..::|.||....|..||.:|..:||||.::......|..|..|.
Human   503 --HDLVLIRLKKKGDRCATRSQFVQPICLPEPGSTFPAGHKCQIAGWGHLDENVSGYSSSLREAL 565

  Fly   535 LDLVPADECNASFAEQPSANRTLRRGVIASQLCAADKNQRKDACQGDSGGPLILEIDDVDGTYSI 599
            :.||...:|        |:.......:..:.|||...:.:.|||||||||||..|   .:|...:
Human   566 VPLVADHKC--------SSPEVYGADISPNMLCAGYFDCKSDACQGDSGGPLACE---KNGVAYL 619

  Fly   600 VGVISSGFGCA-TKTPGLYTRVSSFLDYIEGIVWPSNR 636
            .|:||.|.||. ...||:||||::::|:|...:.|..|
Human   620 YGIISWGDGCGRLHKPGVYTRVANYVDWINDRIRPPRR 657

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hayan	NP_001097020.1	CLIP	32..80	CDD:197829
		Tryp_SPc	385..630	CDD:238113	80/265 (30%)
HGFAC	NP_001284368.1	PRK14954	<32..>100	CDD:184918
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	64..102
		FN2	102..148	CDD:128373
		EGF_CA	162..197	CDD:238011
		FN1	200..240	CDD:238018
		EGF_CA	245..278	CDD:238011
		Kringle	286..367	CDD:395005
		Tryp_SPc	415..650	CDD:238113	80/264 (30%)