Protein Alignment Hayan and Tmprss13

DIOPT Version :10

• Sequence 1: NP_001097020.1
• Gene: Hayan / 32831
• FlyBaseID: FBgn0030925
• Length: 637
• Species: Drosophila melanogaster
• Sequence 2: XP_006510195.1
• Gene: Tmprss13 / 214531
• MGIID: 2682935
• Length: 561
• Species: Mus musculus
• Alignment Length: 590
• Identity: 135/590 - (22%)
• Similarity: 207/590 - (35%)
• Gaps: 185/590 - (31%)

  Fly   169 KTPTHESMKMPTHESMKLPTHEPMKLPIQSVGAWGIAPSKTQPIASTQRSFMEPEWGREPRIVNR 233
            :||...|   |...|       |.:.|.|:      :|::|.|.||..|:..:....|.|    .
Mouse    13 RTPPQAS---PARTS-------PARAPPQA------SPARTPPQASPTRTPPQASPARAP----P 57

  Fly   234 PLTTP-RSRPQR-------PNNS---------NFNTNPSPNNNNLIHLVNDRLREQG---MQIEP 278
            |..:| |:.|.|       |:.|         :.:|..||..   ::||  |....|   ::..|
Mouse    58 PQASPARASPARASLARAPPSRSSSGRSSSARSASTTSSPTR---VYLV--RATPVGAVPIRASP 117

  Fly   279 AREVPMVLQTTPTP----------------------------------------TPAPTPTQLID 303
            ||..|....|..:|                                        |.:|..|.:
Mouse   118 ARSAPATRATRESPGLSFPKFSWQETQRQLPLIGCVILLISLVISLILLYGGRETQSPRGTAV-- 180

  Fly   304 PFEPYRFRGQDRDKDTQPQE--------------------------------------------- 323
                |.:||....|..:|.|
Mouse   181 ----YFWRGHTGIKYKEPLESCPIHAVRCDGVVDCKMKSDELGCVRFDWDKSLLKVYSGSSGEWL 241

  Fly   324 -----PWNDVSN-----NLDADPA-----------PSIFNPAETRPTTPNPNPSRVNLPEKERPS 367
                 .|||..:     .|..|.|           .|.|..:|.. ||...:..|...|.:...|
Mouse   242 PVCSSSWNDTDSKRTCQQLGFDSAYRTTEVAHRDITSSFLLSEYN-TTIQESLYRSQCPSRRYVS 305

  Fly   368 VAACEKIRSGGKPLTVHILDGERVDRGVYPHMAAIAYNSFGSAAFRCGGSLIASRFVLTAAHC-- 430
            : .|.  ..|.:.:|..|:.|.......:|...::   .||:... |||:||.:::|||||||
Mouse   306 L-QCS--HCGLRAMTGRIVGGALTSESKWPWQVSL---HFGTTHI-CGGTLIDAQWVLTAAHCFF 363

  Fly   431 VNSDDSTPSF-VRLGALNIEN-PEPGYQDINVIDVQIHPDYSGSSKYYDIAILQLAEDAKESDVI 493
            |..:.....: |..|..|:.. ||..    ::..:.|:.:|:.....||||:::|::....|..|
Mouse   364 VTREKLLEGWKVYAGTSNLHQLPEAA----SISQIIINGNYTDEQDDYDIALIRLSKPLTLSAHI 424

  Fly   494 RPACLYTDRSDPPANYKYFVAGWGVMNVTNRAVSKILLRAALDLVPADECNASFAEQPSANRTLR 558
            .||||.........|...::.|:|....|:...|..|....::|:...:||........
Mouse   425 HPACLPMHGQTFGLNETCWITGFGKTKETDEKTSPFLREVQVNLIDFKKCNDYLVYDSY------ 483

  Fly   559 RGVIASQLCAADKNQRKDACQGDSGGPLILEIDDVDGTYSIVGVISSGFGCATKT-PGLYTRVSS 622
              :....:||.|....:|:|||||||||:.|   .:..:.:.||.|.|.||..|. ||:||:|:.
Mouse   484 --LTPRMMCAGDLRGGRDSCQGDSGGPLVCE---QNNRWYLAGVTSWGTGCGQKNKPGVYTKVTE 543

  Fly   623 FLDYI 627
            .|.:|
Mouse   544 VLPWI 548

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hayan	NP_001097020.1	CLIP	32..80	CDD:197829
		Tryp_SPc	385..630	CDD:238113	73/248 (29%)
Tmprss13	XP_006510195.1	PHA03378	<6..>122	CDD:223065	33/133 (25%)
		SRCR_2	225..315	CDD:464747	16/93 (17%)
		Tryp_SPc	319..548	CDD:214473	72/247 (29%)