DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Hayan and Prss8

DIOPT Version :9

Sequence 1:	NP_001097020.1	Gene:	Hayan / 32831	FlyBaseID:	FBgn0030925	Length:	637	Species:	Drosophila melanogaster
Sequence 2:	NP_620191.1	Gene:	Prss8 / 192107	RGDID:	619973	Length:	342	Species:	Rattus norvegicus

Alignment Length:	280	Identity:	82/280 - (29%)
Similarity:	126/280 - (45%)	Gaps:	32/280 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly   356 SRVNLPEKERPSVAACEKIRSGGKPLTVHILDGERVDRGVYPHMAAIAYNSFGSAAFRCGGSLIA 420
            ||:.....|    |:|      |..:...|..|.....|.:|...:|.||    ....|||||::
  Rat    26 SRIGADGTE----ASC------GAVIQPRITGGGSAKPGQWPWQVSITYN----GVHVCGGSLVS 76

  Fly   421 SRFVLTAAHCVNSDDSTPSF-VRLGALNIENPEPGYQDINVIDVQIHPDYSGSSKYYDIAILQLA 484
            :::|::||||...:.|...: |:|||..:::.........|..:..|..|.......|||:::|:
  Rat    77 NQWVVSAAHCFPREHSKEEYEVKLGAHQLDSFSNDIVVHTVAQIISHSSYREEGSQGDIALIRLS 141

  Fly   485 EDAKESDVIRPACLYTDRSDPPANYKYFVAGWG-VMNVTNRAVSKILLRAALDLVPADECNASF- 547
            .....|..|||.||....:..|......|.||| |....:....:.|.:..:.|:..:.|:..:
  Rat   142 SPVTFSRYIRPICLPAANASFPNGLHCTVTGWGHVAPSVSLQTPRPLQQLEVPLISRETCSCLYN 206

  Fly   548 ----AEQPSANRTLRRGVIASQLCAADKNQRKDACQGDSGGPLILEIDDVDGTYSIVGVISSGFG 608
                .|:|   .|:::    ..|||......||||||||||||...|   ||.:.:.|::|.|..
  Rat   207 INAVPEEP---HTIQQ----DMLCAGYVKGGKDACQGDSGGPLSCPI---DGLWYLAGIVSWGDA 261

  Fly   609 C-ATKTPGLYTRVSSFLDYI 627
            | |...||:||..|::..:|
  Rat   262 CGAPNRPGVYTLTSTYASWI 281

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Hayan	NP_001097020.1	CLIP	32..80	CDD:197829
		Tryp_SPc	384..627	CDD:214473	75/250 (30%)
		Tryp_SPc	385..630	CDD:238113	76/251 (30%)
Prss8	NP_620191.1	Tryp_SPc	44..281	CDD:214473	75/250 (30%)
Prss8	NP_620191.1	Tryp_SPc	45..284	CDD:238113	76/251 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910