Protein Alignment Hayan and TMPRSS11B

DIOPT Version :10

• Sequence 1: NP_001097020.1
• Gene: Hayan / 32831
• FlyBaseID: FBgn0030925
• Length: 637
• Species: Drosophila melanogaster
• Sequence 2: NP_872308.2
• Gene: TMPRSS11B / 132724
• HGNCID: 25398
• Length: 416
• Species: Homo sapiens
• Alignment Length: 289
• Identity: 92/289 - (31%)
• Similarity: 139/289 - (48%)
• Gaps: 38/289 - (13%)

  Fly   352 NPNPSRVNLPEKERPSVAACEKIRSG--GKPLTVHILDGERVD------RGVYPHMAAIAYNSFG 408
            |..|:.:.|.|   .|.||.|.:.:.  |:.:...|:.|.::.      .|.:|..|::.:
Human   147 NAVPASIKLME---ISKAASEMLTNNCCGRQVANSIITGNKIVNGKSSLEGAWPWQASMQW---- 204

  Fly   409 SAAFRCGGSLIASRFVLTAAHCV----NSDDSTPSFVRLGALNIENPEPGYQDINVIDVQIHPDY 469
            .....||.|||:||::|:||||.    ||.|.|.:|    .:.:..|   |....|.::..|.:|
Human   205 KGRHYCGASLISSRWLLSAAHCFAKKNNSKDWTVNF----GIVVNKP---YMTRKVQNIIFHENY 262

  Fly   470 SGSSKYYDIAILQLAEDAKESDVIRPACLYTDRSDPPANYKYFVAGWGVMNVTNRAVSKILLRAA 534
            |....:.|||::||||:...::.||..||...:.....|....|.|||.:.: |.:...||....
Human   263 SSPGLHDDIALVQLAEEVSFTEYIRKICLPEAKMKLSENDNVVVTGWGTLYM-NGSFPVILQEDF 326

  Fly   535 LDLVPADECNASFAEQPSANRTLRRGVIASQLCAADKNQRKDACQGDSGGPLILEIDDVDGTYSI 599
            |.::....||||:|.......|:        |||...:...||||.|||||  |...|....:.:
Human   327 LKIIDNKICNASYAYSGFVTDTM--------LCAGFMSGEADACQNDSGGP--LAYPDSRNIWHL 381

  Fly   600 VGVISSGFGCATKT-PGLYTRVSSFLDYI 627
            ||::|.|.||..|. ||:||||:|:.::|
Human   382 VGIVSWGDGCGKKNKPGVYTRVTSYRNWI 410

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hayan	NP_001097020.1	CLIP	32..80	CDD:197829
		Tryp_SPc	385..630	CDD:238113	83/254 (33%)
TMPRSS11B	NP_872308.2	SEA	45..142	CDD:460188
		Tryp_SPc	185..413	CDD:238113	81/248 (33%)