Protein Alignment Hayan and KLK8

DIOPT Version :10

• Sequence 1: NP_001097020.1
• Gene: Hayan / 32831
• FlyBaseID: FBgn0030925
• Length: 637
• Species: Drosophila melanogaster
• Sequence 2: NP_653088.1
• Gene: KLK8 / 11202
• HGNCID: 6369
• Length: 305
• Species: Homo sapiens
• Alignment Length: 315
• Identity: 91/315 - (28%)
• Similarity: 136/315 - (43%)
• Gaps: 52/315 - (16%)

  Fly   327 DVSNNLDADPAPSI-FNPAETRPTTPN--PNPSRVN-LPEKERPSVAACEKIRSGGKPLTVHILD 387
            |:...|.|:..|.: .||  ..|:.|:  |...|.| ||.....|.|..:|           :|.
Human    29 DLLTKLYAENLPCVHLNP--QWPSQPSHCPRGWRSNPLPPAAGHSRAQEDK-----------VLG 80

  Fly   388 GERVDRGVYPHMAAIAYNSFGSAAFRCGGSLIASRFVLTAAHCVNSDDSTPSF-VRLGALNIENP 451
            |........|..||:    |......|||.|:...:|||||||     ..|.: ||||..:::|.
Human    81 GHECQPHSQPWQAAL----FQGQQLLCGGVLVGGNWVLTAAHC-----KKPKYTVRLGDHSLQNK 136

  Fly   452 EPGYQDINVIDVQIHPDYSGS---SKYYDIAILQLAEDAKESDVIRPACLYTDRSDPPANYKYFV 513
            :...|:|.|:....||.|:.|   ...:|:.:|||.:.|.....::|..| .|....|.. |..|
Human   137 DGPEQEIPVVQSIPHPCYNSSDVEDHNHDLMLLQLRDQASLGSKVKPISL-ADHCTQPGQ-KCTV 199

  Fly   514 AGWGVMNVTNRAVSKILLRAALDLVPADECNASFAEQPSANRTLRRGVIASQLCAADKNQRKDAC 578
            :|||.:..........|..|.:.:.|..:|..::.           |.|...:..|..::..|.|
Human   200 SGWGTVTSPRENFPDTLNCAEVKIFPQKKCEDAYP-----------GQITDGMVCAGSSKGADTC 253

  Fly   579 QGDSGGPLILEIDDVDGTYSIVGVISSGFG-CA-TKTPGLYTRVSSFLDYIEGIV 631
            ||||||||:     .||  ::.|:.|.|.. |. :..||:||.:..:||:|:.|:
Human   254 QGDSGGPLV-----CDG--ALQGITSWGSDPCGRSDKPGVYTNICRYLDWIKKII 301

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hayan	NP_001097020.1	CLIP	32..80	CDD:197829
		Tryp_SPc	385..630	CDD:238113	74/250 (30%)
KLK8	NP_653088.1	Tryp_SPc	77..297	CDD:214473	74/259 (29%)