Protein Alignment Hayan and proc.2

DIOPT Version :10

• Sequence 1: NP_001097020.1
• Gene: Hayan / 32831
• FlyBaseID: FBgn0030925
• Length: 637
• Species: Drosophila melanogaster
• Sequence 2: NP_001120289.1
• Gene: proc.2 / 100145345
• XenbaseID: XB-GENE-5882297
• Length: 681
• Species: Xenopus tropicalis
• Alignment Length: 689
• Identity: 175/689 - (25%)
• Similarity: 252/689 - (36%)
• Gaps: 202/689 - (29%)

  Fly    30 DPCQVRSDIPGIC--------------LSSSACENIR--GYLKSG-----------TLSTSQVPS 67
            :|||    ..|||              .|...|||.|  .:.|:|           :||.|...:
 Frog    88 NPCQ----NGGICQQYHYSYTCLCPPSYSGRYCENERYECWYKNGGCWQYCTDTAQSLSVSCSCA 148

  Fly    68 CGFGAREEIICCPTVA---CCATDRGREVQFHATSSERSSLPEPKREPTPEPEPL---------P 120
            .|:..:|:...|...|   |           ..|:|...||.:|..:.|   :|:         |
 Frog   149 QGYTLQEDGKKCAKSAPFPC-----------GLTASLTRSLFDPVLDST---DPVATVRSLLDKP 199

  Fly   121 PTTTEGKRERESRLDENQNFFDFNKLLSTTVKPQKTHESLKLPTQESMKTPTHESMKMPTHESMK 185
            .::.||....|:           .::|                 |:......|.|     :|:.:
 Frog   200 TSSREGNMGNEN-----------GRIL-----------------QDRESARAHSS-----NETSE 231

  Fly   186 LPTHEPMKLP--IQSVGAWGIA------PSKTQPIASTQRSFMEPEWGR-------EPRIVNRPL 235
            ..|..|:...  :.:|.|.|.:      ||..:.| ||.|:  |...|:       |.|..||..
 Frog   232 NRTDTPLAWTDNVGNVSAGGDSMGSTAFPSVDRNI-STNRT--EETEGKSQGNRTIEARPTNRSA 293

  Fly   236 -----------TTPRSRPQRPNNSNFNTNPSPNNNNLIHLVNDRLREQGMQIEPAREVP--MVLQ 287
                       .|..|..|..|.|..:.: |.|.......|::.:..|.| |..:.:.|  .:|.
 Frog   294 ESNADTGWAHNKTDTSERQSKNESAESVS-SQNETTKSRQVDENVWIQSM-IRNSTKAPDTEILS 356

  Fly   288 TT----PTPTPAPTPTQLIDPFEPYRFRGQDRDKDTQPQEPWNDVSNNLDADPAPSIFNPAETRP 348
            |.    ||.|.....|:.          ||. |..|..::|.|..|  ||.:...:....|.|..
 Frog   357 TNLGDKPTETGGMNSTEW----------GQG-DDPTAEKKPINKTS--LDHNEIGASVRAARTGT 408

  Fly   349 T---------TPNPNPSRVNLPEKERPSVAACEKIRSGGKPLTVHILDGERVDRGVYPHMAAIAY 404
            :         ..:..|...|.|:.:                  |.|:.|.|.:.|..|....|..
 Frog   409 SKSVWEENHGLASVEPDDYNTPDGD------------------VRIVGGMRCELGQCPWQVLIRN 455

  Fly   405 N-SFGSAAFRCGGSLIASRFVLTAAHCVNSDDSTPSFVRLGALNIENPEPGYQDINVIDVQIHPD 468
            | .||.    ||||||:||:||:||||..|  ..|..|.:|..:....:...|.|.|:.|..||:
 Frog   456 NRGFGF----CGGSLISSRWVLSAAHCFES--QIPHHVTIGDYDTYRRDMDEQKIAVLQVFSHPN 514

  Fly   469 YSGSSKYYDIAILQLAEDAKESDVIRPACLYTDRSDPPANYKYF--------VAGWGVMNVTNRA 525
            |......:|||:|.|...|...:..||.||     ..|...|..        |:|||...... .
 Frog   515 YLAEFYDHDIALLFLRSPAMFGEYSRPICL-----PNPGLGKMLTQEGQTGQVSGWGATRQFG-P 573

  Fly   526 VSKILLRAALDLVPADECNASFAEQPSANRTLRRGVIASQLCAADKNQRKDACQGDSGGPLILEI 590
            .::.||:..|.:|..:.|.||.....:.|          ..||..|...||||.||||||..:..
 Frog   574 YTRFLLKVRLPIVSQETCMASTENILTGN----------MFCAGYKEGVKDACSGDSGGPFAVLF 628

  Fly   591 DDVDGTYSIVGVISSGFGCATKTP-GLYTRVSSFLDYIE 628
            .|   |:.:|||:|.|.|||.|.. |:||||::::.:|:
 Frog   629 HD---TWFLVGVVSWGDGCAEKGKYGVYTRVANYMPWIK 664

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hayan	NP_001097020.1	CLIP	32..80	CDD:197829	17/74 (23%)
		Tryp_SPc	385..630	CDD:238113	88/254 (35%)
proc.2	NP_001120289.1	GLA	19..80	CDD:214503
		EGF_CA	81..117	CDD:238011	7/32 (22%)
		FXa_inhibition	123..160	CDD:464251	7/36 (19%)
		Tryp_SPc	436..666	CDD:238113	88/254 (35%)