DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG15056 and SKP2A

DIOPT Version :9

Sequence 1:	NP_573291.1	Gene:	CG15056 / 32824	FlyBaseID:	FBgn0030918	Length:	399	Species:	Drosophila melanogaster
Sequence 2:	NP_001321134.1	Gene:	SKP2A / 838740	AraportID:	AT1G21410	Length:	360	Species:	Arabidopsis thaliana

Alignment Length:	284	Identity:	57/284 - (20%)
Similarity:	112/284 - (39%)	Gaps:	79/284 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly   109 EIALEGFQLTQYKWFNAPETSFSNLTYVSLRRCQLNDENLV-------GWEFLTHLETLDLRYND 166
            ::.:||..:.:  |.:.|......:  :||    ::|.|::       ||.
plant    17 KMKMEGISIKE--WKDIPVELLMRI--LSL----VDDRNVIVASGVCTGWR-------------- 59

  Fly   167 RLTGSCLMSLPTSLLSLYITGCRNLCPNQLIFLNRIPRLRELRASDLMPGGHWHIYRDLVLACPL 231
                   .::...|..|.::.|.|.. |.|: |:.:|:
plant    60 -------DAISFGLTRLRLSWCNNNM-NSLV-LSLVPK--------------------------- 88

  Fly   232 LVMVEISICSLNRDEYRLGELRYLQSLVIKAHSTDTI----RCKVSDWMLISLL-DVPFLRNLMF 291
              .|::...:|.:|:.:| |...::::....|....:    ..|::|..|.:|. ..|.|..|..
plant    89 --FVKLQTLNLRQDKPQL-EDNAVEAIANHCHELQELDLSKSLKITDRSLYALAHGCPDLTKLNL 150

  Fly   292 SDAPSGFVSANALSIISRF-RQLRVLKMPN--QPYRPNDLLRL-RNLTFLETLDLSNSPYITNEV 352
            |...|  .|..|::.::|| |:|:||.:..  :....|.|..: .|...:::|:|.....|:::.
plant   151 SGCTS--FSDTAIAYLTRFCRKLKVLNLCGCVKAVTDNALEAIGNNCNQMQSLNLGWCENISDDG 213

  Fly   353 VIELVIGIPNLSVLIVQGCPLLTN 376
            |:.|..|.|:|..|.:.||.|:|:
plant   214 VMSLAYGCPDLRTLDLCGCVLITD 237

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15056	NP_573291.1	leucine-rich repeat	133..156	CDD:275381	6/29 (21%)
		leucine-rich repeat	157..179	CDD:275381	0/21 (0%)
		leucine-rich repeat	180..204	CDD:275381	7/23 (30%)
		leucine-rich repeat	205..231	CDD:275381	0/25 (0%)
		leucine-rich repeat	232..285	CDD:275381	10/57 (18%)
		leucine-rich repeat	286..326	CDD:275381	12/42 (29%)
		AMN1	306..>376	CDD:187754	21/73 (29%)
		leucine-rich repeat	337..362	CDD:275381	6/24 (25%)
SKP2A	NP_001321134.1	F-box-like	28..>63	CDD:403981	8/61 (13%)
		leucine-rich repeat	66..91	CDD:275381	8/55 (15%)
		leucine-rich repeat	92..118	CDD:275381	4/26 (15%)
		AMN1	<115..264	CDD:187754	34/125 (27%)
		leucine-rich repeat	119..144	CDD:275381	4/24 (17%)
		leucine-rich repeat	145..170	CDD:275381	8/26 (31%)
		leucine-rich repeat	171..197	CDD:275381	6/25 (24%)
		leucine-rich repeat	198..223	CDD:275381	6/24 (25%)
		leucine-rich repeat	224..249	CDD:275381	6/14 (43%)
		leucine-rich repeat	250..272	CDD:275381
		leucine-rich repeat	294..313	CDD:275381
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1947
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900