DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG15056 and AT5G27920

DIOPT Version :9

Sequence 1:	NP_573291.1	Gene:	CG15056 / 32824	FlyBaseID:	FBgn0030918	Length:	399	Species:	Drosophila melanogaster
Sequence 2:	NP_568502.1	Gene:	AT5G27920 / 832858	AraportID:	AT5G27920	Length:	642	Species:	Arabidopsis thaliana

Alignment Length:	375	Identity:	81/375 - (21%)
Similarity:	138/375 - (36%)	Gaps:	108/375 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly    94 EDFIRLMSIRLTKVNEIALEGFQLTQYKWFNAPETSFSNLTYVSLRRCQLNDENLV--------- 149
            :||:|:.|:..|.:..:.:|......:|        :.||:.:.|..|...|:::|
plant    36 KDFLRVDSLTRTTIRILRVEFLPTLLFK--------YPNLSSLDLSVCPKLDDDVVLRLALDGAI 92

  Fly   150 -------------------GWEFLTH----LETLDLR----YNDR-------LTG-------SCL 173
                               |.|.|..    ||.:|:.    :.||       .||       .||
plant    93 STLGIKSLNLSRSTAVRARGLETLARMCHALERVDVSHCWGFGDREAAALSSATGLRELKMDKCL 157

  Fly   174 MSLPTSLLSLYITGCRNLCPNQLIFLNRIPRL---------RELRASDLMPGGHWHIYRDLVLAC 229
             ||....|:..:.||.||....|.:...|..|         :.|::.|:   .:..|..|.:.:.
plant   158 -SLSDVGLARIVVGCSNLNKISLKWCMEISDLGIDLLCKICKGLKSLDV---SYLKITNDSIRSI 218

  Fly   230 PLLVMVEI---SICSLNRDEYRLGELRYLQSLVIKAHSTDTIRC-KVSDWMLISLL-DVPFLRNL 289
            .|||.:|:   ..|.|..|    |.|::|::........|..|| :||...|||:: ..|.::.|
plant   219 ALLVKLEVLDMVSCPLIDD----GGLQFLENGSPSLQEVDVTRCDRVSLSGLISIVRGHPDIQLL 279

  Fly   290 MFSDAPSGFVSANALSIISRFRQLRVLKMPNQPYRPNDLLRL----------------------- 331
            ..|...|. ||.:.|..|...:.|:.:.:.......:.|:.|
plant   280 KASHCVSE-VSGSFLKYIKGLKHLKTIWIDGAHVSDSSLVSLSSSCRSLMEIGLSRCVDVTDIGM 343

  Fly   332 ----RNLTFLETLDLSNSPYITNEVVIELVIGIPNLSVLIVQGCPLLTNR 377
                ||...|:||:|:...::|:..:..:.....||..|.::.|.|:|.:
plant   344 ISLARNCLNLKTLNLACCGFVTDVAISAVAQSCRNLGTLKLESCHLITEK 393

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15056	NP_573291.1	leucine-rich repeat	133..156	CDD:275381	8/50 (16%)
		leucine-rich repeat	157..179	CDD:275381	11/39 (28%)
		leucine-rich repeat	180..204	CDD:275381	7/23 (30%)
		leucine-rich repeat	205..231	CDD:275381	5/34 (15%)
		leucine-rich repeat	232..285	CDD:275381	17/57 (30%)
		leucine-rich repeat	286..326	CDD:275381	8/39 (21%)
		AMN1	306..>376	CDD:187754	16/96 (17%)
		leucine-rich repeat	337..362	CDD:275381	5/24 (21%)
AT5G27920	NP_568502.1	AMN1	65..261	CDD:187754	45/203 (22%)
		leucine-rich repeat	67..96	CDD:275381	5/28 (18%)
		leucine-rich repeat	97..122	CDD:275381	3/24 (13%)
		leucine-rich repeat	123..147	CDD:275381	5/23 (22%)
		leucine-rich repeat	148..173	CDD:275381	7/25 (28%)
		leucine-rich repeat	174..199	CDD:275381	4/24 (17%)
		AMN1	192..393	CDD:187754	46/208 (22%)
		leucine-rich repeat	200..222	CDD:275381	5/24 (21%)
		leucine-rich repeat	224..249	CDD:275381	7/28 (25%)
		leucine-rich repeat	250..298	CDD:275381	16/48 (33%)
		leucine-rich repeat	299..352	CDD:275381	5/52 (10%)
		AMN1	<329..464	CDD:187754	13/65 (20%)
		leucine-rich repeat	353..378	CDD:275381	5/24 (21%)
		leucine-rich repeat	379..404	CDD:275381	5/15 (33%)
		AMN1	405..>567	CDD:187754
		leucine-rich repeat	405..429	CDD:275381
		leucine-rich repeat	430..455	CDD:275381
		leucine-rich repeat	456..481	CDD:275381
		leucine-rich repeat	482..506	CDD:275381
		leucine-rich repeat	507..532	CDD:275381
		leucine-rich repeat	533..558	CDD:275381
		leucine-rich repeat	559..583	CDD:275381
		leucine-rich repeat	584..609	CDD:275381
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1947
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1282076at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910