DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG15056 and EBF2

DIOPT Version :9

Sequence 1:	NP_573291.1	Gene:	CG15056 / 32824	FlyBaseID:	FBgn0030918	Length:	399	Species:	Drosophila melanogaster
Sequence 2:	NP_197917.1	Gene:	EBF2 / 832607	AraportID:	AT5G25350	Length:	623	Species:	Arabidopsis thaliana

Alignment Length:	428	Identity:	87/428 - (20%)
Similarity:	140/428 - (32%)	Gaps:	165/428 - (38%)

- Green bases have known domain annotations that are detailed below.

  Fly    30 SFAASCDMFENIYVRSSPLRLSRVVNLEEMIEFSLLE-----TKL---FVELSGSDIEIIRGGPH 86
            :.|..|....:|.:||.| |:.     ::.:.|.|.:     ||:   .:.:||..:.:|
plant   239 AIARRCVNLRSISIRSCP-RIG-----DQGVAFLLAQAGSYLTKVKLQMLNVSGLSLAVI----- 292

  Fly    87 TPMFSHFEDFIRLMSIRLTKVNEIALEGFQLTQYKWF---------------------------- 123
                .|:.          ..|.::.|.|.|....|.|
plant   293 ----GHYG----------AAVTDLVLHGLQGVNEKGFWVMGNAKGLKKLKSLSVMSCRGMTDVGL 343

  Fly   124 NAPETSFSNLTYVSLRRCQL-NDENLVGW-EFLTHLETLDLRYNDRLT----------------- 169
            .|......:|.:|||.:|.| :.:.||.. :....||:|.|....|:.
plant   344 EAVGNGCPDLKHVSLNKCLLVSGKGLVALAKSALSLESLKLEECHRINQFGLMGFLMNCGSKLKA 408

  Fly   170 ---GSCL--------MSLP----TSLLSLYITGCRNLCPNQLIFLNRIPRLRELRASDLMPGGHW 219
               .:||        .|||    :||.||.|..|.......|.||                |...
plant   409 FSLANCLGISDFNSESSLPSPSCSSLRSLSIRCCPGFGDASLAFL----------------GKFC 457

  Fly   220 HIYRDLVLACPLLVMVEISICSLN--RDEYRLGELRYLQSL---VIKAHSTDTIRCKVSDWMLIS 279
            |..:|            :.:|.||  .|   .|....|||.   ::|.:.::.|  .||| ..:|
plant   458 HQLQD------------VELCGLNGVTD---AGVRELLQSNNVGLVKVNLSECI--NVSD-NTVS 504

  Fly   280 LLDVPFLRNL--MFSDAPSGFVSANALSIISRFRQLRVLKMPNQPYRPNDLLRLRNLTFLETLDL 342
            .:.|...|.|  :..|......:|:.:::....            |..||            ||:
plant   505 AISVCHGRTLESLNLDGCKNITNASLVAVAKNC------------YSVND------------LDI 545

  Fly   343 SNSPYITNEVVIELVIGIP---NLSVLIVQGCPLLTNR 377
            ||:  :.::..|:.:...|   ||.||.:.||..:|::
plant   546 SNT--LVSDHGIKALASSPNHLNLQVLSIGGCSSITDK 581

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15056	NP_573291.1	leucine-rich repeat	133..156	CDD:275381	8/24 (33%)
		leucine-rich repeat	157..179	CDD:275381	10/53 (19%)
		leucine-rich repeat	180..204	CDD:275381	8/23 (35%)
		leucine-rich repeat	205..231	CDD:275381	3/25 (12%)
		leucine-rich repeat	232..285	CDD:275381	15/57 (26%)
		leucine-rich repeat	286..326	CDD:275381	5/41 (12%)
		AMN1	306..>376	CDD:187754	15/72 (21%)
		leucine-rich repeat	337..362	CDD:275381	6/27 (22%)
EBF2	NP_197917.1	F-box	54..>92	CDD:279040
		AMN1	<138..268	CDD:187754	8/34 (24%)
		leucine-rich repeat	169..194	CDD:275381
		leucine-rich repeat	195..220	CDD:275381
		leucine-rich repeat	221..246	CDD:275381	2/6 (33%)
		leucine-rich repeat	247..278	CDD:275381	9/36 (25%)
		leucine-rich repeat	279..326	CDD:275381	10/65 (15%)
		leucine-rich repeat	327..352	CDD:275381	1/24 (4%)
		leucine-rich repeat	353..378	CDD:275381	8/24 (33%)
		leucine-rich repeat	379..402	CDD:275381	5/22 (23%)
		leucine-rich repeat	406..459	CDD:275381	15/68 (22%)
		leucine-rich repeat	407..433	CDD:275381	5/25 (20%)
		AMN1	435..>582	CDD:187754	45/207 (22%)
		leucine-rich repeat	460..511	CDD:275381	16/68 (24%)
		leucine-rich repeat	487..512	CDD:275381	7/27 (26%)
		leucine-rich repeat	514..537	CDD:275381	3/22 (14%)
		leucine-rich repeat	540..566	CDD:275381	8/39 (21%)
		leucine-rich repeat	567..595	CDD:275381	6/15 (40%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1947
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1282076at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910