DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG15056 and GRH1

DIOPT Version :9

Sequence 1:	NP_573291.1	Gene:	CG15056 / 32824	FlyBaseID:	FBgn0030918	Length:	399	Species:	Drosophila melanogaster
Sequence 2:	NP_567255.1	Gene:	GRH1 / 828045	AraportID:	AT4G03190	Length:	585	Species:	Arabidopsis thaliana

Alignment Length:	441	Identity:	89/441 - (20%)
Similarity:	148/441 - (33%)	Gaps:	179/441 - (40%)

- Green bases have known domain annotations that are detailed below.

  Fly    20 LKQLDLKSRISFA-----------ASCDMFENIYVRSSPL---RLSRVVNLEEMIEFSLLETKLF 70
            ::.|.||.:..||           .:....|.:..:||.|   |:.|:|..:|.:|
plant    64 MRSLTLKGKPHFADYNLVPDGWGGYAWPWIEAMAAKSSSLEEIRMKRMVVTDECLE--------- 119

  Fly    71 VELSGSDIEIIRGGPHTPMFSHFEDFIRLMSIRLTKVNEIALEGFQLTQYKWFNAPETSFSNLTY 135
             :::.|                |:||..|:   ||.....:.:|..        |...:..||..
plant   120 -KIAAS----------------FKDFKVLV---LTSCEGFSTDGIA--------AIAATCRNLRV 156

  Fly   136 VSLRRCQLNDENLVGWEFL-------THLETLDLRYNDRLTGSC------------LMSLPTSLL 181
            :.||.|.:.|   :|.::|       |.|.:||.        ||            |:|...:|.
plant   157 LELRECIVED---LGGDWLSYFPESSTSLVSLDF--------SCLDSEVKISDLERLVSRSPNLK 210

  Fly   182 SLYITGCRNLCPNQLIFLNR-IPRLRELR----ASDLMP-------------------GGHWHIY 222
            ||.:.....|  :.|:.|.| .|:|.||.    |:.|.|                   .|.|.:.
plant   211 SLKLNPAVTL--DGLVSLLRCAPQLTELGTGSFAAQLKPEAFSKLSEAFSNCKQLQSLSGLWDVL 273

  Fly   223 RD----LVLACPLLVMVEISICSLNRDEYRLGELRYLQSLVIKAHSTDTIRC-KVSDWMLISLLD 282
            .:    |...||.|..:.:|..::     |:.:|..|..           || |:....::.|::
plant   274 PEYLPALYSVCPGLTSLNLSYATV-----RMPDLVELLR-----------RCSKLQKLWVMDLIE 322

  Fly   283 VPFLRNLMFSDAPSGFVSANALSIISRFRQLRVLKMPNQPYRPNDLLRLRNLTFLETLDLSNSPY 347
            ...|..:              .|.....|:|||  .|::|                .||.:|.|
plant   323 DKGLEAV--------------ASYCKELRELRV--FPSEP----------------DLDATNIP- 354

  Fly   348 ITNEVVIELVIGIPNLSVLIVQGCPLLTNRVYLDAELA-------SKKRSN 391
            :|.:       |:    |.:.:||..|.:.:|...:..       ::||.|
plant   355 LTEQ-------GL----VFVSKGCRKLESVLYFCVQFTNAALFTIARKRPN 394

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15056	NP_573291.1	leucine-rich repeat	133..156	CDD:275381	7/29 (24%)
		leucine-rich repeat	157..179	CDD:275381	7/33 (21%)
		leucine-rich repeat	180..204	CDD:275381	7/24 (29%)
		leucine-rich repeat	205..231	CDD:275381	10/52 (19%)
		leucine-rich repeat	232..285	CDD:275381	9/53 (17%)
		leucine-rich repeat	286..326	CDD:275381	8/39 (21%)
		AMN1	306..>376	CDD:187754	16/69 (23%)
		leucine-rich repeat	337..362	CDD:275381	6/24 (25%)
GRH1	NP_567255.1	F-box_5	4..43	CDD:408301
		Transp_inhibit	62..108	CDD:408562	9/43 (21%)
		leucine-rich repeat	103..127	CDD:275381	8/49 (16%)
		AMN1	<112..267	CDD:187754	42/204 (21%)
		leucine-rich repeat	128..153	CDD:275381	6/35 (17%)
		leucine-rich repeat	154..208	CDD:275381	15/64 (23%)
		leucine-rich repeat	209..232	CDD:275381	7/24 (29%)
		leucine-rich repeat	233..279	CDD:275381	8/45 (18%)
		AMN1	280..488	CDD:187754	34/175 (19%)
		leucine-rich repeat	287..311	CDD:275381	7/39 (18%)
		leucine-rich repeat	312..335	CDD:275381	3/36 (8%)
		leucine-rich repeat	336..369	CDD:275381	15/62 (24%)
		leucine-rich repeat	370..394	CDD:275381	4/23 (17%)
		leucine-rich repeat	395..429	CDD:275381	89/441 (20%)
		leucine-rich repeat	430..453	CDD:275381
		leucine-rich repeat	454..478	CDD:275381
		leucine-rich repeat	479..498	CDD:275381
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1947
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1282076at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910