DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG15056 and TIR1

DIOPT Version :9

Sequence 1:	NP_573291.1	Gene:	CG15056 / 32824	FlyBaseID:	FBgn0030918	Length:	399	Species:	Drosophila melanogaster
Sequence 2:	NP_567135.1	Gene:	TIR1 / 825473	AraportID:	AT3G62980	Length:	594	Species:	Arabidopsis thaliana

Alignment Length:	477	Identity:	101/477 - (21%)
Similarity:	167/477 - (35%)	Gaps:	175/477 - (36%)

- Green bases have known domain annotations that are detailed below.

  Fly    25 LKSRISFAASCDMFENIYVRSSPLRLSRVVNLEEMIEFSLLE------TKLFVE--LSGSDIEII 81
            ::.||:.:...::.|:::   |.::|.:..|...::..|..|      .|:|:.  .:.|...:|
plant     1 MQKRIALSFPEEVLEHVF---SFIQLDKDRNSVSLVCKSWYEIERWCRRKVFIGNCYAVSPATVI 62

  Fly    82 RGGPHTPMFS-----HFEDFIRLMSIRLTKVNEIALEGFQLTQYKWFNAPETSFSNLTYVSLRRC 141
            |..|......     ||.||            .:..:|:....|.|..|..:|::.|..:.|:|.
plant    63 RRFPKVRSVELKGKPHFADF------------NLVPDGWGGYVYPWIEAMSSSYTWLEEIRLKRM 115

  Fly   142 QLNDE--NLVGWEF-------------------------LTHLETLDLRYN--DRLTGSCLMSLP 177
            .:.|:  .|:...|                         ..:|:.||||.:  |.::|..|...|
plant   116 VVTDDCLELIAKSFKNFKVLVLSSCEGFSTDGLAAIAATCRNLKELDLRESDVDDVSGHWLSHFP 180

  Fly   178 ---TSLLSL----------------YITGCRNLCPNQL----------IFLNRIPRLRELRAS-- 211
               |||:||                .:|.|.||...:|          ..|.|.|:|.||...
plant   181 DTYTSLVSLNISCLASEVSFSALERLVTRCPNLKSLKLNRAVPLEKLATLLQRAPQLEELGTGGY 245

  Fly   212 ------DLMPG---------------GHWHIYRDLVLACPLLVMVEISICSLNRDEYRLGELRYL 255
                  |:..|               |.|.       |.|..:....|:||      ||..|..
plant   246 TAEVRPDVYSGLSVALSGCKELRCLSGFWD-------AVPAYLPAVYSVCS------RLTTLNL- 296

  Fly   256 QSLVIKAHSTDTIRCKVSDWMLISLL-DVPFLRNLMFSDAPSGFVSANALSIISR----FRQLRV 315
                  :::|      |..:.|:.|| ..|.|:.|...|    ::....|.:::.    .|:|||
plant   297 ------SYAT------VQSYDLVKLLCQCPKLQRLWVLD----YIEDAGLEVLASTCKDLRELRV 345

  Fly   316 LKMPNQPY--RPNDLLRLRNLTFLETLDLSNSPYITNEVVIELVIGIPNL-SVLIVQGCPLLTNR 377
              .|::|:  .||..|                   |.:.::.:.:|.|.| |||..  |..:||
plant   346 --FPSEPFVMEPNVAL-------------------TEQGLVSVSMGCPKLESVLYF--CRQMTN- 386

  Fly   378 VYLDAELASKKRSNGNMVKVQL 399
                |.|.:..|:..||.:.:|
plant   387 ----AALITIARNRPNMTRFRL 404

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15056	NP_573291.1	leucine-rich repeat	133..156	CDD:275381	6/49 (12%)
		leucine-rich repeat	157..179	CDD:275381	9/26 (35%)
		leucine-rich repeat	180..204	CDD:275381	10/49 (20%)
		leucine-rich repeat	205..231	CDD:275381	8/48 (17%)
		leucine-rich repeat	232..285	CDD:275381	11/53 (21%)
		leucine-rich repeat	286..326	CDD:275381	10/45 (22%)
		AMN1	306..>376	CDD:187754	17/76 (22%)
		leucine-rich repeat	337..362	CDD:275381	2/24 (8%)
TIR1	NP_567135.1	F-box_5	8..47	CDD:408301	6/41 (15%)
		Transp_inhibit	66..112	CDD:408562	11/57 (19%)
		leucine-rich repeat	107..131	CDD:275381	6/23 (26%)
		AMN1	<116..>224	CDD:187754	22/107 (21%)
		leucine-rich repeat	132..157	CDD:275381	0/24 (0%)
		leucine-rich repeat	158..212	CDD:275381	16/53 (30%)
		leucine-rich repeat	213..286	CDD:275381	14/79 (18%)
		AMN1	286..>400	CDD:187754	39/164 (24%)
		leucine-rich repeat	291..315	CDD:275381	7/36 (19%)
		leucine-rich repeat	316..339	CDD:275381	4/26 (15%)
		leucine-rich repeat	340..373	CDD:275381	11/53 (21%)
		leucine-rich repeat	374..398	CDD:275381	10/30 (33%)
		leucine-rich repeat	399..433	CDD:275381	2/6 (33%)
		leucine-rich repeat	434..457	CDD:275381
		leucine-rich repeat	458..482	CDD:275381
		leucine-rich repeat	483..507	CDD:275381
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1947
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1282076at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910