DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG15056 and EBF1

DIOPT Version :9

Sequence 1:	NP_573291.1	Gene:	CG15056 / 32824	FlyBaseID:	FBgn0030918	Length:	399	Species:	Drosophila melanogaster
Sequence 2:	NP_565597.1	Gene:	EBF1 / 817087	AraportID:	AT2G25490	Length:	628	Species:	Arabidopsis thaliana

Alignment Length:	412	Identity:	80/412 - (19%)
Similarity:	151/412 - (36%)	Gaps:	112/412 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly    17 LDVLKQLDLKSRISFAASCDMFENIYVRSSPL-RLSRVVNLEEMIEFSLLETKLFVELSGSDIEI 80
            |:...::..:..::.|.||...:::.:::.|| |...:.:|......||.:.||.: |:.:|:.:
plant   236 LEACSRIGDEGLLAIARSCSKLKSVSIKNCPLVRDQGIASLLSNTTCSLAKLKLQM-LNVTDVSL 299

  Fly    81 IRGGPHTPMFSHFEDFIRLMSIRLTKVNEIALEGFQLTQYKWFNAPETSFSNLTYVSLRRCQ--- 142
                   .:..|:.  :.:..:.|..::.::.:||      |..........|..:::..||
plant   300 -------AVVGHYG--LSITDLVLAGLSHVSEKGF------WVMGNGVGLQKLNSLTITACQGVT 349

  Fly   143 ------------------------LNDENLVGW-EFLTHLETLDLRYNDRLT-----GSCLMSLP 177
                                    |:|..||.: :....||:|.|....|:|     || |::..
plant   350 DMGLESVGKGCPNMKKAIISKSPLLSDNGLVSFAKASLSLESLQLEECHRVTQFGFFGS-LLNCG 413

  Fly   178 TSLLSLYITGC---RNLCPNQLIFLNRIPRLRELRASDLMPGGHWHIYRDLVLA-----CPLLVM 234
            ..|.:..:..|   |:|... |...:....||.|...: .||     :.|..||     ||.|
plant   414 EKLKAFSLVNCLSIRDLTTG-LPASSHCSALRSLSIRN-CPG-----FGDANLAAIGKLCPQL-- 469

  Fly   235 VEISICSLNRDEYRLGELRYLQSLVIK------AHSTDTIRCKV---SDWMLISLLDVPFLRNLM 290
            .:|.:|.| :.....|.|..:||.::|      ::.||.:...:   :.|.| .:|::
plant   470 EDIDLCGL-KGITESGFLHLIQSSLVKINFSGCSNLTDRVISAITARNGWTL-EVLNI------- 525

  Fly   291 FSDAPSGFVSANALSIISRFRQLRVLKMPNQPYRPNDLLRLRNLTFLETLDLSNSPYITNEVVIE 355
              |..|....|:.:||.:                        |...|..||:|......:.:...
plant   526 --DGCSNITDASLVSIAA------------------------NCQILSDLDISKCAISDSGIQAL 564

  Fly   356 LVIGIPNLSVLIVQGCPLLTNR 377
            .......|.:|.|.||.::|::
plant   565 ASSDKLKLQILSVAGCSMVTDK 586

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15056	NP_573291.1	leucine-rich repeat	133..156	CDD:275381	7/50 (14%)
		leucine-rich repeat	157..179	CDD:275381	9/26 (35%)
		leucine-rich repeat	180..204	CDD:275381	5/26 (19%)
		leucine-rich repeat	205..231	CDD:275381	9/30 (30%)
		leucine-rich repeat	232..285	CDD:275381	14/61 (23%)
		leucine-rich repeat	286..326	CDD:275381	5/39 (13%)
		AMN1	306..>376	CDD:187754	11/69 (16%)
		leucine-rich repeat	337..362	CDD:275381	4/24 (17%)
EBF1	NP_565597.1	F-box-like	64..101	CDD:372399
		AMN1	<149..298	CDD:187754	14/62 (23%)
		leucine-rich repeat	179..204	CDD:275381
		leucine-rich repeat	205..230	CDD:275381
		leucine-rich repeat	231..256	CDD:275381	4/19 (21%)
		leucine-rich repeat	257..283	CDD:275381	4/25 (16%)
		leucine-rich repeat	284..308	CDD:275381	6/33 (18%)
		leucine-rich repeat	309..336	CDD:275381	4/32 (13%)
		leucine-rich repeat	337..362	CDD:275381	3/24 (13%)
		leucine-rich repeat	363..388	CDD:275381	4/24 (17%)
		leucine-rich repeat	416..442	CDD:275381	5/26 (19%)
		AMN1	440..611	CDD:187754	40/190 (21%)
		leucine-rich repeat	443..468	CDD:275381	9/30 (30%)
		leucine-rich repeat	469..492	CDD:275381	7/25 (28%)
		leucine-rich repeat	493..519	CDD:275381	3/25 (12%)
		leucine-rich repeat	520..545	CDD:275381	8/58 (14%)
		leucine-rich repeat	546..571	CDD:275381	4/24 (17%)
		leucine-rich repeat	572..591	CDD:275381	6/15 (40%)
		leucine-rich repeat	598..619	CDD:275381
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1947
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1282076at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910