DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment CG15056 and fbxl16

DIOPT Version :9

Sequence 1:NP_573291.1 Gene:CG15056 / 32824 FlyBaseID:FBgn0030918 Length:399 Species:Drosophila melanogaster
Sequence 2:NP_001188265.1 Gene:fbxl16 / 797939 ZFINID:ZDB-GENE-120215-180 Length:493 Species:Danio rerio


Alignment Length:380 Identity:90/380 - (23%)
Similarity:152/380 - (40%) Gaps:102/380 - (26%)


- Green bases have known domain annotations that are detailed below.


  Fly     3 FISFS--VISRFDFFWLDVLKQLDLKSRISFAASCDMFENIY------VRSSPLRLSRVVN--LE 57
            |:|..  .:..|..|.|..:..||:         |:..:| |      |:|..|:.|.:.:  ||
Zfish   171 FVSLQAFALRGFQAFCLVGVSDLDI---------CEFIDN-YPLSKKGVKSVSLKRSTITDAGLE 225

  Fly    58 EMIEFSLLETKLFVELSGSDIEIIRGGPHTPMFSHF------------EDFIRLMSIRLTKVNEI 110
            .|:|  .::..:.:||||.: :....|..:.:.:..            :|.|..:|..|..::|:
Zfish   226 VMLE--QMQGLMHLELSGCN-DFTEAGLWSSLNARLTSLSVSDCINVADDAIAAISQLLPNLSEL 287

  Fly   111 ALEGFQLTQ--YKWFNAPETSFSNLTYVSLRRCQLNDENLVGWEFLTHLETLDLRYNDRLTG--S 171
            :|:.:.:|.  ..:|.|.: .::..| :.|..|         ||...|             |  :
Zfish   288 SLQAYHVTDTAMAYFTAKQ-GYTTHT-LRLNSC---------WEITNH-------------GVVN 328

  Fly   172 CLMSLPTSLLSLYITGCRNLCPN--QLIFLNRIPRLRELRASDLMPGGHWHIYRDLVLACPLLVM 234
            .:.||| :|.||.::||..:..:  :|:..|    ||:||:.||    .|         ||.:..
Zfish   329 MVHSLP-NLTSLSLSGCSKITDDGVELVAEN----LRKLRSLDL----SW---------CPRITD 375

  Fly   235 VEISICSLNRDEYRLGELRYLQSLVIKAHSTDTIRC-KVSDWMLISLLDVPFLRNLMFSDAPSGF 298
            :.:        ||...:|..|:.||:.       || :::|..|..|..:..||:|.......  
Zfish   376 MAL--------EYIACDLHKLEELVLD-------RCVRITDTGLGYLSTMSTLRSLYLRWCCQ-- 423

  Fly   299 VSANALSIISRFRQLRVLKMPNQP-YRPNDLLRLRNLTFLETLDLSNSPYITNEV 352
            |....|..:...|.||:|.:...| .....|..|..|..||.|:|:|.|..|.|:
Zfish   424 VQDFGLQHLYGMRSLRLLSLAGCPLLTTTGLSGLIQLQDLEELELTNCPGATAEL 478

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG15056NP_573291.1 leucine-rich repeat 133..156 CDD:275381 5/22 (23%)
leucine-rich repeat 157..179 CDD:275381 4/23 (17%)
leucine-rich repeat 180..204 CDD:275381 7/25 (28%)
leucine-rich repeat 205..231 CDD:275381 8/25 (32%)
leucine-rich repeat 232..285 CDD:275381 11/53 (21%)
leucine-rich repeat 286..326 CDD:275381 10/40 (25%)
AMN1 306..>376 CDD:187754 16/48 (33%)
leucine-rich repeat 337..362 CDD:275381 8/16 (50%)
fbxl16NP_001188265.1 leucine-rich repeat 209..233 CDD:275381 8/25 (32%)
AMN1 215..446 CDD:187754 65/292 (22%)
leucine-rich repeat 234..253 CDD:275381 5/19 (26%)
leucine-rich repeat 258..283 CDD:275381 4/24 (17%)
leucine-rich repeat 284..308 CDD:275381 5/24 (21%)
leucine-rich repeat 309..335 CDD:275381 10/49 (20%)
leucine-rich repeat 336..361 CDD:275381 8/28 (29%)
leucine-rich repeat 362..387 CDD:275381 10/45 (22%)
leucine-rich repeat 388..412 CDD:275381 8/30 (27%)
leucine-rich repeat 413..437 CDD:275381 5/25 (20%)
leucine-rich repeat 438..457 CDD:275381 5/18 (28%)
leucine-rich repeat 463..488 CDD:275381 8/16 (50%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D1282076at2759
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
11.010

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