DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment CG15056 and Fbxl18

DIOPT Version :10

Sequence 1:NP_573291.1 Gene:CG15056 / 32824 FlyBaseID:FBgn0030918 Length:399 Species:Drosophila melanogaster
Sequence 2:NP_001385803.1 Gene:Fbxl18 / 678726 RGDID:1596958 Length:707 Species:Rattus norvegicus


Alignment Length:511 Identity:99/511 - (19%)
Similarity:158/511 - (30%) Gaps:222/511 - (43%)


- Green bases have known domain annotations that are detailed below.


  Fly    28 RISFAASC-DMFENIYVRSSP------------LRLSRVVNLEE-------------------MI 60
            |:|...|| ....::.:..||            ..||||..|::                   ::
  Rat   124 RLSRVLSCLQRLRSLAIDVSPGFDASQLSSECKATLSRVQELKQTLFTPSYGVVPCCASLQKLLL 188

  Fly    61 EFSLLE-TKLFVELSGSDIEIIRGGPHTPMFSHFEDFIRLMS--------IRL------------ 104
            .|.:|: |:....|||   :::.|..:.|.:.:...|...::        :||            
  Rat   189 YFEILDRTREGAVLSG---QLMVGQSNVPHYQNLRVFYARLAPGYINQEVVRLYLAVLSDRTPEN 250

  Fly   105 -----------------TK------VNEIALEGFQLTQYKWFNA----PETSFSNLTYVSLRRCQ 142
                             ||      ...:||:..||.: .|.|.    ....|:|..|.|..||.
  Rat   251 LHAFLISVPGSFAESGATKNLLDSMARNVALDALQLPK-SWLNGSTLLQHMKFNNPFYFSFSRCT 314

  Fly   143 LNDENLVGWEFLTHLETL-----DLRYNDRLTGSCLMSLPTSLLSLYITGCRNLCPNQLIFLNRI 202
            |:..:|:        :.|     |||               ||.||.::||.: |      |:..
  Rat   315 LSGGHLI--------QRLINGGKDLR---------------SLASLNLSGCVH-C------LSAD 349

  Fly   203 PRLRELRASDLMPGGHWHIYRDLVLACPLLVMVEIS-------------ICSLNRDEYRLGELRY 254
            ..||  :|.|.:...   |...||.:|..|..:.:|             :|.|      |..|.:
  Rat   350 SLLR--KAEDDIDSS---ILETLVESCCNLHHLNLSAAHHHSSDGLGRHLCQL------LARLCH 403

  Fly   255 LQSLVIKAHSTDTIRCKVSD--------------------------------------------- 274
            |:||.:..       |.|:|                                             
  Rat   404 LRSLSLPV-------CSVADSAPRPDRAPAPPAMHAVPRGFGKKVRIGVQTCPNPFVGQSAPQPA 461

  Fly   275 ---WMLISLLDVPFLRNLMFSDAPSGFVSA---------NALSIISRFRQLRVLKMPNQPYRPND 327
               |.|:..|  |||.:|..  ..|.|.||         |:|...||          .|....::
  Rat   462 SVFWSLLKKL--PFLEHLEL--IGSNFSSAMPRNEPAIRNSLPPCSR----------AQNVGDSE 512

  Fly   328 LLRLRNLTFLETLDLSNSP-YITNEVVIELVIGIPNLSVLIVQGCPLLTNRVYLDA 382
            :..:..||||..|.|:..| .:|...::.:.:....|..|.:....::...||:.|
  Rat   513 VAAIGQLTFLRHLTLAQLPGMLTGSGLVSIGLQCQQLQSLSLANLGMMGKVVYMPA 568

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG15056NP_573291.1 leucine-rich repeat 133..156 CDD:275381 6/22 (27%)
leucine-rich repeat 157..179 CDD:275381 4/26 (15%)
leucine-rich repeat 180..204 CDD:275381 7/23 (30%)
leucine-rich repeat 205..231 CDD:275381 8/25 (32%)
leucine-rich repeat 232..285 CDD:275381 15/113 (13%)
leucine-rich repeat 286..326 CDD:275381 11/48 (23%)
AMN1 306..>376 CDD:187754 13/70 (19%)
leucine-rich repeat 337..362 CDD:275381 5/25 (20%)
Fbxl18NP_001385803.1 F-box_FBXL18 17..60 CDD:438900
FBXL18_LRR 74..664 CDD:466163 99/511 (19%)
leucine-rich repeat 334..373 CDD:275381 15/50 (30%)
leucine-rich repeat 374..403 CDD:275381 6/34 (18%)
leucine-rich repeat 404..473 CDD:275381 9/77 (12%)
leucine-rich repeat 522..548 CDD:275381 5/25 (20%)
leucine-rich repeat 549..578 CDD:275381 5/20 (25%)
leucine-rich repeat 579..604 CDD:275381
leucine-rich repeat 605..629 CDD:275381
Blue background indicates that the domain is not in the aligned region.

Return to query results.
Submit another query.