DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG15056 and Fbxo39

DIOPT Version :9

Sequence 1:	NP_573291.1	Gene:	CG15056 / 32824	FlyBaseID:	FBgn0030918	Length:	399	Species:	Drosophila melanogaster
Sequence 2:	XP_006533964.2	Gene:	Fbxo39 / 628100	MGIID:	3505735	Length:	480	Species:	Mus musculus

Alignment Length:	292	Identity:	63/292 - (21%)
Similarity:	94/292 - (32%)	Gaps:	86/292 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly   112 LEGFQLTQYKWFNAPETSFSNLTYVSLRRCQLNDENLVGWEFLTHLETLDLRYNDRLTGSCLMSL 176
            ||..::.....:||..|....:|...|..|.....|.:....:.|||...|.:.:.:.||.:.||
Mouse   126 LEHLEIKFLNPYNAVLTKKFQVTMRGLLSCLGKSNNRLRSLSIQHLELDRLVWRNSIRGSLIKSL 190

  Fly   177 P------------TSLLSLYIT---GCRNLCPNQLIFLNRIPRLRELRASDLMPGGHWHIYRDLV 226
            .            .||....:|   ||..|  |.|.::.......||...|.. ..|..:|....
Mouse   191 SFFLKKMGKHLDHLSLKGARLTVEQGCHIL--NSLSYMQNENMASELNIEDFF-SHHLAVYGSSQ 252

  Fly   227 LACPLLVMVEISICSLNRD-----------EYRLGELRYLQSLVIKAHSTDTIRCKVSD------ 274
            ....:.....::..:||.:           |...|.||           |..|:|.|.|
Mouse   253 FNKAMATFRNLTFLTLNYNCISDELLETLSENNAGTLR-----------TMNIKCHVHDPHGQVV 306

  Fly   275 ----WMLI----SLLDVPF----------LRNLMFSDAPSGFVSANALSIISRFRQLRVLKMPNQ 321
                |..:    |.|.|.|          |..::..:.|     ..::|:.|.:     ...|:.
Mouse   307 WGMSWAKLARQASNLKVNFFFERVMKYERLARILLQEIP-----VRSISLRSCY-----FSDPDW 361

  Fly   322 PYRP--NDLL-----RLRNLTF-----LETLD 341
            ..||  .|||     .|:.|||     .|:||
Mouse   362 SMRPTLTDLLPTFRNTLQKLTFEFNNNHESLD 393

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15056	NP_573291.1	leucine-rich repeat	133..156	CDD:275381	4/22 (18%)
		leucine-rich repeat	157..179	CDD:275381	7/33 (21%)
		leucine-rich repeat	180..204	CDD:275381	7/26 (27%)
		leucine-rich repeat	205..231	CDD:275381	5/25 (20%)
		leucine-rich repeat	232..285	CDD:275381	15/77 (19%)
		leucine-rich repeat	286..326	CDD:275381	7/41 (17%)
		AMN1	306..>376	CDD:187754	14/48 (29%)
		leucine-rich repeat	337..362	CDD:275381	3/5 (60%)
Fbxo39	XP_006533964.2	F-box-like	53..94	CDD:372399
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1947
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900