DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG15056 and fbxl7

DIOPT Version :9

Sequence 1:NP_573291.1 Gene:CG15056 / 32824 FlyBaseID:FBgn0030918 Length:399 Species:Drosophila melanogaster
Sequence 2:NP_001073511.1 Gene:fbxl7 / 569430 ZFINID:ZDB-GENE-061215-122 Length:489 Species:Danio rerio


Alignment Length:375 Identity:76/375 - (20%)
Similarity:134/375 - (35%) Gaps:113/375 - (30%)


- Green bases have known domain annotations that are detailed below.


  Fly    75 GSDIEIIRGGPHTPMFSHFEDFIRLMSIRLTKVNEIALEGFQLTQYKWFNAPETSFSNLTYVSLR 139
            |:.::|:      |..:..:.|..|.:.:|.:...:.        .:|:|               
Zfish   109 GAPVDIL------PDHAFLQIFTHLPTNQLCRCARVC--------RRWYN--------------- 144

  Fly   140 RCQLNDENLVGWE---FLTHLETLDLRYNDR----LTGSCLMSLPTSLL---SLYITGCRNLCPN 194
                     :.|:   :.|...|.|:.:.||    ||.......|...|   ::.::|||.|...
Zfish   145 ---------LAWDPRLWRTIRLTGDVLHVDRALRVLTRRLCQDTPNVCLTVETVMVSGCRRLTDR 200

  Fly   195 QLIFL-NRIPRLRELRASDLMPGGHWHIYRDLVLACPLLVMVEISIC------SLNRD-EYRLGE 251
            .|..: ...|.||.|..:......:..:: ::|..||.|..:::|.|      ||.|| ..:|..
Zfish   201 GLYTVAQSCPELRRLEVAGCYNVSNEAVF-EVVSRCPNLEHLDVSGCSKVTCISLTRDVSVKLSP 264

  Fly   252 L-------RYLQSL-----------VIKAHSTDTI-----RC-KVSD-WMLISLLDVPFLRNLMF 291
            |       |:|...           .|.||.|...     || :::| .:...::..|.:|.|..
Zfish   265 LHGQQISIRFLDMTDCFALEDEGLHTIAAHCTQLTHLYLRRCVRLTDEGLRFLVIYCPGVRELSV 329

  Fly   292 SDAPSGFVSANALSIISRFR-QLRVLKMPN--------QPYRPNDLLRLRNLTF----------- 336
            ||.  .|:|...|..|::.. :||.|.:.:        ..|......|||.|..           
Zfish   330 SDC--RFISDFGLREIAKLEGRLRYLSIAHCSRITDVGVRYVAKYCSRLRYLNARGCEGLTDHGI 392

  Fly   337 ---------LETLDLSNSPYITNEVVIELVIGIPNLSVLIVQGCPLLTNR 377
                     |::||:...|.:::..:.:|.:...||..|.::.|..:|.|
Zfish   393 EHLAKSCLKLKSLDIGKCPLVSDAGLEQLALNSFNLKRLSLKSCESITGR 442

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG15056NP_573291.1 leucine-rich repeat 133..156 CDD:275381 1/25 (4%)
leucine-rich repeat 157..179 CDD:275381 7/25 (28%)
leucine-rich repeat 180..204 CDD:275381 6/27 (22%)
leucine-rich repeat 205..231 CDD:275381 5/25 (20%)
leucine-rich repeat 232..285 CDD:275381 18/84 (21%)
leucine-rich repeat 286..326 CDD:275381 12/48 (25%)
AMN1 306..>376 CDD:187754 18/98 (18%)
leucine-rich repeat 337..362 CDD:275381 5/24 (21%)
fbxl7NP_001073511.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..76
F-box-like 112..158 CDD:289689 9/83 (11%)
leucine-rich repeat 127..151 CDD:275381 5/55 (9%)
leucine-rich repeat 152..185 CDD:275381 8/32 (25%)
LRR 1 168..193 4/24 (17%)
AMN1 <183..364 CDD:187754 43/183 (23%)
leucine-rich repeat 186..211 CDD:275381 5/24 (21%)
LRR 2 194..219 8/24 (33%)
leucine-rich repeat 212..233 CDD:275381 3/21 (14%)
LRR 3 220..245 4/25 (16%)
leucine-rich repeat 238..271 CDD:275381 9/32 (28%)
LRR 4 251..279 8/27 (30%)
leucine-rich repeat 272..297 CDD:275381 5/24 (21%)
LRR 5 280..305 4/24 (17%)
AMN1 295..463 CDD:187754 32/150 (21%)
leucine-rich repeat 298..323 CDD:275381 3/24 (13%)
LRR 6 306..331 5/24 (21%)
leucine-rich repeat 324..349 CDD:275381 8/26 (31%)
LRR 7 332..357 7/26 (27%)
leucine-rich repeat 350..375 CDD:275381 4/24 (17%)
LRR 8 358..383 5/24 (21%)
leucine-rich repeat 376..401 CDD:275381 3/24 (13%)
LRR 9 384..409 3/24 (13%)
leucine-rich repeat 402..427 CDD:275381 5/24 (21%)
LRR 10 410..435 5/24 (21%)
leucine-rich repeat 428..451 CDD:275381 5/15 (33%)
LRR 11 436..461 3/7 (43%)
leucine-rich repeat 454..478 CDD:275381
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C170588104
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG1947
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
21.830

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