DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG15056 and Ppa

DIOPT Version :9

Sequence 1:	NP_573291.1	Gene:	CG15056 / 32824	FlyBaseID:	FBgn0030918	Length:	399	Species:	Drosophila melanogaster
Sequence 2:	NP_001261138.1	Gene:	Ppa / 37602	FlyBaseID:	FBgn0020257	Length:	562	Species:	Drosophila melanogaster

Alignment Length:	294	Identity:	66/294 - (22%)
Similarity:	123/294 - (41%)	Gaps:	84/294 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly   133 LTYVSLRRC-QLNDE---NLVGWEFLT-----HLETLDL----RYNDRLTGSCLMSLPTSLLSLY 184
            |.:::||.| .::|:   :|.|:...|     .||.|.|    |.:|...|.....| |||.|:.
  Fly   315 LKHLNLRSCWHISDQGIGHLAGFSRETAEGNLQLEYLGLQDCQRLSDEALGHIAQGL-TSLKSIN 378

  Fly   185 ITGCRNLCPNQLIFLNRIPRLRE--LRASD---------LMPGGHWHIYRDLVLACPLLVMVEIS 238
            ::.|.::..:.|..|.|:|:|.:  ||:.|         |..||..            :..:::|
  Fly   379 LSFCVSVTDSGLKHLARMPKLEQLNLRSCDNISDIGMAYLTEGGSG------------INSLDVS 431

  Fly   239 ICSLNRDEYRLGELRYLQSLVIKAHSTDTIRCKVSDWMLISLLDVPFLRNLMFSDAPSGFVSANA 303
            .|....|:    .|.::...:.:..|....:|:::|..::.:                    |.|
  Fly   432 FCDKISDQ----ALTHIAQGLYRLRSLSLNQCQITDHGMLKI--------------------AKA 472

  Fly   304 LSIISRFRQLRVLKMPNQPYRPND--LLRL-RNLTFLETLDLSNSPYITNEVVIELVIGIP---- 361
            |      .:|..|.: .|..|..|  |..| .:||.|:|:||.....:::: .|::::.:|
  Fly   473 L------HELENLNI-GQCSRITDKGLQTLAEDLTNLKTIDLYGCTQLSSK-GIDIIMKLPKLQK 529

  Fly   362 -NLSVLIVQGCPLLTNRVYLDAE-LASKKRSNGN 393
             ||.:.:|:.|      |:.|.. .|:|:.:.|:
  Fly   530 LNLGLWLVRXC------VHHDCNACAAKEAARGS 557

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15056	NP_573291.1	leucine-rich repeat	133..156	CDD:275381	8/31 (26%)
		leucine-rich repeat	157..179	CDD:275381	8/25 (32%)
		leucine-rich repeat	180..204	CDD:275381	6/23 (26%)
		leucine-rich repeat	205..231	CDD:275381	7/36 (19%)
		leucine-rich repeat	232..285	CDD:275381	7/52 (13%)
		leucine-rich repeat	286..326	CDD:275381	7/39 (18%)
		AMN1	306..>376	CDD:187754	19/77 (25%)
		leucine-rich repeat	337..362	CDD:275381	6/29 (21%)
Ppa	NP_001261138.1	F-box-like	149..190	CDD:289689
		AMN1	<226..>334	CDD:187754	5/18 (28%)
		leucine-rich repeat	236..256	CDD:275381
		leucine-rich repeat	263..288	CDD:275381
		leucine-rich repeat	289..314	CDD:275381
		leucine-rich repeat	315..347	CDD:275381	8/31 (26%)
		AMN1	347..524	CDD:187754	48/221 (22%)
		leucine-rich repeat	348..373	CDD:275381	8/25 (32%)
		leucine-rich repeat	374..398	CDD:275381	6/23 (26%)
		leucine-rich repeat	399..424	CDD:275381	7/24 (29%)
		leucine-rich repeat	425..450	CDD:275381	4/28 (14%)
		leucine-rich repeat	451..475	CDD:275381	6/49 (12%)
		leucine-rich repeat	476..501	CDD:275381	8/25 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45457937
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1947
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1282076at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.750