DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG15056 and Fbl6

DIOPT Version :9

Sequence 1:	NP_573291.1	Gene:	CG15056 / 32824	FlyBaseID:	FBgn0030918	Length:	399	Species:	Drosophila melanogaster
Sequence 2:	NP_610665.2	Gene:	Fbl6 / 36201	FlyBaseID:	FBgn0033609	Length:	720	Species:	Drosophila melanogaster

Alignment Length:	347	Identity:	77/347 - (22%)
Similarity:	134/347 - (38%)	Gaps:	90/347 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    98 RLMSIRLTKVNEIALEGFQLTQY------KWFNAPETSFSNLTYVSLRRCQLNDEN--------- 147
            |.:|:|.|....:.|..:...:|      |||  .:...|..|.:::...:::|.|
  Fly   326 RQVSLRPTLWRTMDLTTWVKEKYRTELKLKWF--VDNRCSACTDLNVSNWKISDINCFLAKLSSG 388

  Fly   148 --------LVGWEFLT--HLETL--DLRYNDRLTGSCLMSLPTSL-LSLYITGCRNLCPNQLIFL 199
                    |.||:..|  ||..|  ::....||.   |.|:...: .|....|..:|| |.|..:
  Fly   389 CPNLAGITLSGWKGFTSDHLTYLVDNMHKLQRLD---LSSINVEMNASKSAVGVNSLC-NALQTM 449

  Fly   200 NRIPRLRELRASDLMPGGHWHIYRDLVLACPLLVMVEIS-------------ICSLNRDEYRLGE 251
            .  .||..|..:.....|...|...|...||.|.::::|             |..|.|...:|..
  Fly   450 G--SRLTHLYLAHNRLAGIPQIVGILSTHCPNLTLLDLSNVTTQATSHGVLHIEKLQRGCQKLKV 512

  Fly   252 LRYLQSLVIKAHSTDTIRCKVSDWMLISLLDVPFLRNLMFSDAPSGFVSANALSIISRFRQLRVL 316
            ||     |..:|.|.      |...:..::|.|            ||.....||:.:...:.|::
  Fly   513 LR-----VTNSHITP------STASMQEIMDSP------------GFPELEELSVAALTDESRII 554

  Fly   317 KMPNQPYRPNDLLR--LRNLTFLETLDLSNSPYITNEVVIELVIGIP--NLSVLIVQGCPLLTNR 377
            .        :|.|:  |::.:.|:.||:.|...:|:|.:|.|    |  ::..|.:.||. :|..
  Fly   555 S--------DDHLQRILKSSSKLKLLDVRNCTRLTHESLIRL----PAWDIKHLFLSGCS-VTRD 606

  Fly   378 VYLDAELASKKRSNGNMVKVQL 399
            :....||.:.|.:: :::::.|
  Fly   607 MGSGLELIASKWAH-SLIELDL 627

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15056	NP_573291.1	leucine-rich repeat	133..156	CDD:275381	7/41 (17%)
		leucine-rich repeat	157..179	CDD:275381	6/23 (26%)
		leucine-rich repeat	180..204	CDD:275381	6/24 (25%)
		leucine-rich repeat	205..231	CDD:275381	6/25 (24%)
		leucine-rich repeat	232..285	CDD:275381	13/65 (20%)
		leucine-rich repeat	286..326	CDD:275381	5/39 (13%)
		AMN1	306..>376	CDD:187754	16/73 (22%)
		leucine-rich repeat	337..362	CDD:275381	9/26 (35%)
Fbl6	NP_610665.2	F-box-like	293..341	CDD:289689	4/14 (29%)
		leucine-rich repeat	365..391	CDD:275381	3/25 (12%)
		leucine-rich repeat	392..417	CDD:275381	7/24 (29%)
		leucine-rich repeat	418..445	CDD:275381	8/30 (27%)
		leucine-rich repeat	453..471	CDD:275381	4/17 (24%)
		leucine-rich repeat	480..509	CDD:275381	5/28 (18%)
		leucine-rich repeat	510..538	CDD:275381	11/50 (22%)
		leucine-rich repeat	539..579	CDD:275381	10/47 (21%)
		leucine-rich repeat	580..621	CDD:275381	12/46 (26%)
		leucine-rich repeat	622..649	CDD:275381	1/6 (17%)
		leucine-rich repeat	652..676	CDD:275381
		leucine-rich repeat	677..698	CDD:275381
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1947
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.900