DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG15056 and CG9316

DIOPT Version :9

Sequence 1:	NP_573291.1	Gene:	CG15056 / 32824	FlyBaseID:	FBgn0030918	Length:	399	Species:	Drosophila melanogaster
Sequence 2:	NP_610051.2	Gene:	CG9316 / 35333	FlyBaseID:	FBgn0032878	Length:	448	Species:	Drosophila melanogaster

Alignment Length:	388	Identity:	88/388 - (22%)
Similarity:	130/388 - (33%)	Gaps:	124/388 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly    29 ISFAASCDMFENIYVRSSPLRLSRV----VNLEEMIEFSLLETKLFVELSGSDIEIIRGGPHTPM 89
            ||::.:.|.|....:.|....|.||    ::.|:::.|.:...:
  Fly   142 ISYSNATDEFHYRSIMSKMTHLKRVTIECLDAEDVLNFDMQPNQ--------------------- 185

  Fly    90 FSHFEDFIRLMSIRLTKVNEIALEGFQLTQYKWFNAPETSFSNLTYVSLRRCQLNDENLVGW--- 151
                                 .||.|:|....:.......|.||..:.||.|.|       |
  Fly   186 ---------------------ELEFFELVNGCYTGQNLCGFPNLKTLVLRDCLL-------WNSM 222

  Fly   152 EF---LTHLETLDLRYNDRLTGSCLMSLPTSLLSLYITGCRNL-------CPNQLIFLNRIPRLR 206
            ||   |..|.|||      |...|...:..||.......|.||       |......:..:|:|.
  Fly   223 EFGIPLKSLHTLD------LDDCCFEVMNVSLYQKIAESCTNLVELIFSGCDTNFEVIANLPKLE 281

  Fly   207 ELRASDLMPGGHWHIYRDLVLACPLLVMVEISICSLNRDEYRLGELRYL----QSLVIKAHSTDT 267
            .......|.....:|....|||                 |.|..:|.:|    |..:...|:
  Fly   282 RCTLKTWMTSNELNIGFLTVLA-----------------EKRGNKLTHLHLSGQFNITNEHA--- 326

  Fly   268 IRCKVSDWMLISLLDVPFLRNLMFSDAPSGFVSANALSIISRFRQL---RVLKMPNQPYRPNDLL 329
             ||.   ..|.||.|:.|..|.:..|  ..|...|.||.:.||...   ||:.:        .::
  Fly   327 -RCL---GQLSSLTDLRFSNNDILDD--DHFKFFNDLSQLERFGLTACGRVMDV--------GMM 377

  Fly   330 R-LRNLTFLETLDLSNSPYITNEVVIELVIGIPNLS-----VLIVQGC----PLLTNRVYLDA 382
            | ||....|:.:||::...||.|.||: .||..:..     ||.|:|.    |:||:..|:::
  Fly   378 RMLRKCPQLKVIDLTDCEQITEEFVIQ-AIGFCSKGSGRDVVLNVKGTMIRRPILTHPDYVNS 439

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15056	NP_573291.1	leucine-rich repeat	133..156	CDD:275381	9/28 (32%)
		leucine-rich repeat	157..179	CDD:275381	6/21 (29%)
		leucine-rich repeat	180..204	CDD:275381	5/30 (17%)
		leucine-rich repeat	205..231	CDD:275381	6/25 (24%)
		leucine-rich repeat	232..285	CDD:275381	12/56 (21%)
		leucine-rich repeat	286..326	CDD:275381	10/42 (24%)
		AMN1	306..>376	CDD:187754	23/82 (28%)
		leucine-rich repeat	337..362	CDD:275381	10/24 (42%)
CG9316	NP_610051.2	leucine-rich repeat	208..221	CDD:275381	6/19 (32%)
		leucine-rich repeat	231..258	CDD:275381	9/32 (28%)
		leucine-rich repeat	259..279	CDD:275381	2/19 (11%)
		leucine-rich repeat	280..309	CDD:275381	8/45 (18%)
		AMN1	310..>411	CDD:187754	34/118 (29%)
		leucine-rich repeat	310..334	CDD:275381	7/30 (23%)
		leucine-rich repeat	335..359	CDD:275381	8/25 (32%)
		leucine-rich repeat	360..385	CDD:275381	7/32 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45457953
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1947
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.830