DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG15056 and Fbxl4

DIOPT Version :9

Sequence 1:NP_573291.1 Gene:CG15056 / 32824 FlyBaseID:FBgn0030918 Length:399 Species:Drosophila melanogaster
Sequence 2:NP_001382505.1 Gene:Fbxl4 / 313101 RGDID:1305724 Length:621 Species:Rattus norvegicus


Alignment Length:432 Identity:97/432 - (22%)
Similarity:145/432 - (33%) Gaps:155/432 - (35%)


- Green bases have known domain annotations that are detailed below.


  Fly    51 SRVVNLEEMIEFSLLETKLFVELSGSDIEIIRGGPHTPMFSHFEDFIRLMSIRLTKVNEIALEGF 115
            :.::.||  :..|||:  .:.||   |..::.|....|:.|        :...|..:|::..:.:
  Rat   202 TNLIRLE--VNSSLLD--YYTEL---DAVVLHGTKDKPLLS--------LKTALVDMNDLEDDDY 251

  Fly   116 QLTQYKWFNAPETSFSNLTYVSLRRCQLNDENLVGW----------EFLTHLETLDLRYNDRLTG 170
            :.......:|....||:.|        |.|....|:          ..|.||...||   .||..
  Rat   252 EEKDGCEMDALNKKFSSAT--------LGDGPSNGYFDKLPYELIQLILNHLSLPDL---CRLAQ 305

  Fly   171 SC---------------LMSLP-------TSL------------LSLYITGCR------------ 189
            :|               |...|       |||            |:|..||.|            
  Rat   306 TCRLLHQHCCDPLQYIHLNLQPYWAKLDDTSLEFLQARCALVQWLNLSWTGNRGFISVSGFSRFL 370

  Fly   190 NLCPNQLIFLNRIPRLRELRASDLMPGGHWHIYRDLVL-----ACPLLVMVEISIC-SLNRDEY- 247
            .:|.::|:.|       ||..|        |...|..|     .||.|..:.:|.| .|....: 
  Rat   371 KVCGSELVRL-------ELSCS--------HFLNDACLEVISEMCPNLQDLNLSSCDKLPPQAFG 420

  Fly   248 RLGELRYLQSLVIKAHSTDTIRCKVSDWMLISLLDVPFLRNLMFSDAPSGFVSAN----ALSIIS 308
            .:.:||.|:.|::       .|.||....|:|:|:  |...|......|..:..:    |..|.:
  Rat   421 HIAKLRSLKRLIL-------YRTKVEQTALLSILN--FCAELQHLSLGSCVMIEDYDVIASMIGA 476

  Fly   309 RFRQLRVLKMPNQPYRPNDLLRLRNLT------------FLETLDLSNSPYITNEV--VIELVIG 359
            :.:.||.|          ||.|.:|:|            .||.|||...|.:.:..  ...|...
  Rat   477 KCKSLRTL----------DLWRCKNITENGIAELASGCALLEELDLGWCPTLQSSTGCFARLARQ 531

  Fly   360 IPNLSVLIVQGCPLLTNRVYLDA---ELASKKRSNGNMVKVQ 398
            :|||..|.     |..||...|.   ||||      |..::|
  Rat   532 LPNLQKLF-----LTANRSVCDTDIEELAS------NCTRLQ 562

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG15056NP_573291.1 leucine-rich repeat 133..156 CDD:275381 5/32 (16%)
leucine-rich repeat 157..179 CDD:275381 8/43 (19%)
leucine-rich repeat 180..204 CDD:275381 9/47 (19%)
leucine-rich repeat 205..231 CDD:275381 7/30 (23%)
leucine-rich repeat 232..285 CDD:275381 14/54 (26%)
leucine-rich repeat 286..326 CDD:275381 7/43 (16%)
AMN1 306..>376 CDD:187754 21/83 (25%)
leucine-rich repeat 337..362 CDD:275381 7/26 (27%)
Fbxl4NP_001382505.1 F-box-like 280..318 CDD:403981 8/40 (20%)
leucine-rich repeat 295..317 CDD:275381 6/24 (25%)
leucine-rich repeat 318..340 CDD:275381 5/21 (24%)
leucine-rich repeat 347..376 CDD:275381 6/28 (21%)
leucine-rich repeat 377..402 CDD:275381 9/39 (23%)
AMN1 394..601 CDD:187754 50/199 (25%)
leucine-rich repeat 403..427 CDD:275381 5/23 (22%)
leucine-rich repeat 428..452 CDD:275381 9/32 (28%)
leucine-rich repeat 453..480 CDD:275381 4/26 (15%)
leucine-rich repeat 481..506 CDD:275381 8/34 (24%)
leucine-rich repeat 507..534 CDD:275381 7/26 (27%)
leucine-rich repeat 535..560 CDD:275381 11/35 (31%)
leucine-rich repeat 561..586 CDD:275381 1/2 (50%)
leucine-rich repeat 587..612 CDD:275381
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG1947
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

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