DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG15056 and Fbxl19

DIOPT Version :9

Sequence 1:	NP_573291.1	Gene:	CG15056 / 32824	FlyBaseID:	FBgn0030918	Length:	399	Species:	Drosophila melanogaster
Sequence 2:	XP_006230338.1	Gene:	Fbxl19 / 308999	RGDID:	1310989	Length:	739	Species:	Rattus norvegicus

Alignment Length:	229	Identity:	54/229 - (23%)
Similarity:	80/229 - (34%)	Gaps:	85/229 - (37%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 ISFSVISRFDFFW----LDVLKQLDLKSRISFAASCDMFENIYVRSSPLRLSRVVNLE--EMIEF 62
            :|::.:|:....|    |..|::|.|       :.|.......:.|:||...|:::|.  |.::.
  Rat   535 LSWTGVSKKQLMWLLNRLQGLQELVL-------SGCSWLSVSALGSAPLPALRLLDLRWIEDVKD 592

  Fly    63 SLLETKLFVELSGSDIEIIRGGPHT-PMFSHFEDFIRLMSIRLTKVNEIALEGFQLTQYKWFNAP 126
            |.|.            |::...|.| |..:....       ||..|.|:.|.|.:||.
  Rat   593 SQLR------------ELLLPPPDTKPGQTESRG-------RLQGVAELRLAGLELTD------- 631

  Fly   127 ETSFSNLTYVSLRRCQLNDENLVGWEFLTH---LETLDLRYNDRLTGSC---------LMSLPTS 179
                     .|||.            .|.|   |..|||.:       |         |::.|||
  Rat   632 ---------ASLRL------------LLRHAPQLSALDLSH-------CAHVGDPSVHLLTAPTS 668

  Fly   180 -----LLSLYITGCRNLCPNQLIFLNRIPRLREL 208
                 |:.|.:.||..|..:.|....|.||||.|
  Rat   669 PLRETLVHLNLAGCHRLTDHCLPLFRRCPRLRRL 702

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15056	NP_573291.1	leucine-rich repeat	133..156	CDD:275381	4/22 (18%)
		leucine-rich repeat	157..179	CDD:275381	7/30 (23%)
		leucine-rich repeat	180..204	CDD:275381	7/23 (30%)
		leucine-rich repeat	205..231	CDD:275381	3/4 (75%)
		leucine-rich repeat	232..285	CDD:275381
		leucine-rich repeat	286..326	CDD:275381
		AMN1	306..>376	CDD:187754
		leucine-rich repeat	337..362	CDD:275381
Fbxl19	XP_006230338.1	zf-CXXC	<95..122	CDD:251032
		PHD_FXL19	132..193	CDD:277115
		F-box-like	469..512	CDD:289689
		AMN1	511..710	CDD:187754	54/229 (24%)
		leucine-rich repeat	531..554	CDD:275381	4/18 (22%)
		leucine-rich repeat	555..578	CDD:275381	7/29 (24%)
		leucine-rich repeat	616..643	CDD:275381	12/54 (22%)
		leucine-rich repeat	644..670	CDD:275381	9/32 (28%)
		leucine-rich repeat	674..698	CDD:275381	7/23 (30%)
		leucine-rich repeat	699..723	CDD:275381	3/4 (75%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166346679
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.930