DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG15056 and Fbxl6

DIOPT Version :9

Sequence 1:NP_573291.1 Gene:CG15056 / 32824 FlyBaseID:FBgn0030918 Length:399 Species:Drosophila melanogaster
Sequence 2:NP_038937.2 Gene:Fbxl6 / 30840 MGIID:1354705 Length:535 Species:Mus musculus


Alignment Length:227 Identity:53/227 - (23%)
Similarity:88/227 - (38%) Gaps:58/227 - (25%)


- Green bases have known domain annotations that are detailed below.


  Fly   191 LCPNQLIFLNRIPRLRELRASDLMPGGHW----HIYRDLVLA-CPLLVMVEISICSLNRDEYRLG 250
            |.||         |..:|::..|:   ||    |...:||.. ||.|..:::|.|.....|    
Mouse   180 LVPN---------RFSQLQSLTLI---HWKSQVHSVLELVSKFCPRLTFLKLSDCHTVTAE---- 228

  Fly   251 ELRYLQSLVIKAHSTDTIRCKVSDWMLISLLDVPFLRN----LMFSDAPSGFVSANALSIISRFR 311
            .|..|.....:.||.|.....|....::|.|:....|.    |.:|...:..:.|...:...:.:
Mouse   229 TLVMLARACCQLHSLDLHHSMVESTAVVSFLEEAGSRMRKLWLTYSSQTTAILGALLDNCCPQLQ 293

  Fly   312 QLRV----------LKMPNQPYRPN----DLLRLRNLTF-----------------LETLDLSNS 345
            .|:|          |::|.:..:..    .:|||.||.:                 ||.|.|:.|
Mouse   294 VLQVSTGMNCNNTPLQLPVEALQKGCPQLQVLRLLNLIWLPKPCGRGVPQGPGFPSLEELCLAGS 358

  Fly   346 P--YITNEVVIELVIGIPNLSVLIVQGCPLLT 375
            .  :::|||:..|:...|.|.:|.::||..:|
Mouse   359 TCNFVSNEVLGRLLHRSPKLRMLDLRGCARVT 390

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG15056NP_573291.1 leucine-rich repeat 133..156 CDD:275381
leucine-rich repeat 157..179 CDD:275381
leucine-rich repeat 180..204 CDD:275381 3/12 (25%)
leucine-rich repeat 205..231 CDD:275381 8/30 (27%)
leucine-rich repeat 232..285 CDD:275381 12/52 (23%)
leucine-rich repeat 286..326 CDD:275381 8/53 (15%)
AMN1 306..>376 CDD:187754 24/103 (23%)
leucine-rich repeat 337..362 CDD:275381 9/26 (35%)
Fbxl6NP_038937.2 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..25
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 61..99
F-box-like 105..155 CDD:289689
LRR 1 169..195 6/26 (23%)
AMN1 171..390 CDD:187754 52/225 (23%)
leucine-rich repeat 188..213 CDD:275381 8/27 (30%)
LRR 2 196..221 7/24 (29%)
leucine-rich repeat 214..239 CDD:275381 6/28 (21%)
LRR 3 222..247 7/28 (25%)
leucine-rich repeat 240..291 CDD:275381 10/50 (20%)
LRR 4 273..299 4/25 (16%)
leucine-rich repeat 292..321 CDD:275381 4/28 (14%)
LRR 5 304..329 5/24 (21%)
leucine-rich repeat 322..349 CDD:275381 5/26 (19%)
LRR 6 330..357 5/26 (19%)
AMN1 <349..500 CDD:187754 15/42 (36%)
leucine-rich repeat 350..377 CDD:275381 9/26 (35%)
LRR 7 360..385 7/24 (29%)
leucine-rich repeat 378..401 CDD:275381 5/13 (38%)
LRR 8 386..411 2/5 (40%)
LRR 9 415..441
leucine-rich repeat 434..466 CDD:275381
leucine-rich repeat 467..491 CDD:275381
LRR 10 474..499
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C167843073
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG1947
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.830

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