DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG15056 and Fbxl21

DIOPT Version :9

Sequence 1:	NP_573291.1	Gene:	CG15056 / 32824	FlyBaseID:	FBgn0030918	Length:	399	Species:	Drosophila melanogaster
Sequence 2:	XP_038951543.1	Gene:	Fbxl21 / 306750	RGDID:	1305555	Length:	460	Species:	Rattus norvegicus

Alignment Length:	233	Identity:	46/233 - (19%)
Similarity:	77/233 - (33%)	Gaps:	82/233 - (35%)

- Green bases have known domain annotations that are detailed below.

  Fly   170 GSCLMSLPTSLLSLYITGCRNLCPNQLI--FLNRIPRLRELRASDLMPGGHWHIYRDLVLACPLL 232
            |.|.....|.:||..:..  ...|:.:|  ....:|.:...|||
  Rat    51 GLCTSLRQTQMLSALLDW--GTLPHHVILRIFQYLPLVDRARAS--------------------- 92

  Fly   233 VMVEISIC-SLNR-----DEYRLGELRYLQSL--------------VIKAH-------------S 264
                 |:| |.|.     |.:|..|....||.              :||.|             |
  Rat    93 -----SVCRSWNEVFHIPDLWRKFEFELNQSATSYFKSTHPDLIQQIIKKHAAHLQYVSFKVDSS 152

  Fly   265 TDT-----------IRCKVSDWMLISLLDVPFLRNLMFSDAPSGFVSANALSIISRFRQLRVLKM 318
            |::           :.|.:....|||.....|: |:    ..|.||||..:..::. :.|..:|:
  Rat   153 TESAEAACHILSQLVNCSIQTLGLISTAKPSFM-NM----PKSHFVSALTVVFVNS-KSLSSIKI 211

  Fly   319 PNQPYRPNDL--LRLRNLTFLETLDLSNSPYITNEVVI 354
            .:.|.....|  |...|...|..|.:|:.|:::::.::
  Rat   212 EDTPVDDPSLKILVANNSDTLRLLKMSSCPHVSSDGIL 249

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15056	NP_573291.1	leucine-rich repeat	133..156	CDD:275381
		leucine-rich repeat	157..179	CDD:275381	2/8 (25%)
		leucine-rich repeat	180..204	CDD:275381	4/25 (16%)
		leucine-rich repeat	205..231	CDD:275381	3/25 (12%)
		leucine-rich repeat	232..285	CDD:275381	18/96 (19%)
		leucine-rich repeat	286..326	CDD:275381	9/39 (23%)
		AMN1	306..>376	CDD:187754	10/51 (20%)
		leucine-rich repeat	337..362	CDD:275381	4/18 (22%)
Fbxl21	XP_038951543.1	F-box-like	68..111	CDD:403981	12/70 (17%)
		leucine-rich repeat	206..231	CDD:275381	6/24 (25%)
		leucine-rich repeat	232..257	CDD:275381	4/18 (22%)
		leucine-rich repeat	258..283	CDD:275381
		leucine-rich repeat	284..318	CDD:275381
		leucine-rich repeat	329..365	CDD:275381
		AMN1	<359..>424	CDD:187754
		leucine-rich repeat	366..392	CDD:275381
		leucine-rich repeat	393..418	CDD:275381
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166346659
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1947
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.830