DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG15056 and Fbxo39

DIOPT Version :9

Sequence 1:	NP_573291.1	Gene:	CG15056 / 32824	FlyBaseID:	FBgn0030918	Length:	399	Species:	Drosophila melanogaster
Sequence 2:	NP_001034107.1	Gene:	Fbxo39 / 303287	RGDID:	1311464	Length:	443	Species:	Rattus norvegicus

Alignment Length:	327	Identity:	63/327 - (19%)
Similarity:	102/327 - (31%)	Gaps:	134/327 - (40%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 NFISFSVISRFDFFWLDVLKQLD---LK-SRISFAASCDMFENI-YVRSSPLRLSRVVNLEEMIE 61
            |.|..|:|....||...:.|.||   || :|::....|.:..:: |:|:.  .::..:|:|:
  Rat   143 NSIRGSLIKSLSFFLKKMGKHLDHLSLKGARLTVEQGCHILNSLSYMRNE--NVASELNIED--- 202

  Fly    62 FSLLETKLFVELSGSDIEIIRGGPHTPMFSHFEDFIRLMSIRLTKVNEIALEGFQLTQYKWFNAP 126
                                       .|||                .:|:.|     ...||..
  Rat   203 ---------------------------FFSH----------------HLAVYG-----SSQFNKA 219

  Fly   127 ETSFSNLTYVSLRRCQLNDENL------------------------------VGWEFLTHLETLD 161
            ..:|.|||:::|....::||.|                              :.|..|.. :..:
  Rat   220 MATFHNLTFLTLNYNCISDELLETLSENNAGTLRTMNIKCHVHDPHGQVVWGMSWAKLAR-QASN 283

  Fly   162 LRYN---------DRLTGSCLMSLPT---SLLSLYITG--------CRNLCPNQLIFLNRIPRLR 206
            |:.|         :||....|..:|.   ||.|.|.:.        ..:|.|.   |.|.:.:|.
  Rat   284 LKVNFFFERVMKYERLARILLQEIPVRSISLRSCYFSDPDWSMRPTLTDLLPT---FRNTLQKLT 345

  Fly   207 -ELRASDLMPGGHWHIYRDLVLACPLLVMVEI------------------SICSLNRDEYRLGEL 252
             |...:........|:   |:|||..|...:|                  ..|||...:.|:...
  Rat   346 FEFNNNHESLDEQLHL---LILACRKLFYFKIWAFLDVKFVERILKSQEEGQCSLRTLKVRIYTN 407

  Fly   253 RY 254
            ||
  Rat   408 RY 409

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15056	NP_573291.1	leucine-rich repeat	133..156	CDD:275381	8/52 (15%)
		leucine-rich repeat	157..179	CDD:275381	6/33 (18%)
		leucine-rich repeat	180..204	CDD:275381	7/31 (23%)
		leucine-rich repeat	205..231	CDD:275381	7/26 (27%)
		leucine-rich repeat	232..285	CDD:275381	8/41 (20%)
		leucine-rich repeat	286..326	CDD:275381
		AMN1	306..>376	CDD:187754
		leucine-rich repeat	337..362	CDD:275381
Fbxo39	NP_001034107.1	F-box-like	16..57	CDD:403981
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1947
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900