Protein Alignment CG15056 and FBXL5

DIOPT Version :10

• Sequence 1: NP_573291.1
• Gene: CG15056 / 32824
• FlyBaseID: FBgn0030918
• Length: 399
• Species: Drosophila melanogaster
• Sequence 2: NP_036293.1
• Gene: FBXL5 / 26234
• HGNCID: 13602
• Length: 691
• Species: Homo sapiens
• Alignment Length: 98
• Identity: 30/98 - (30%)
• Similarity: 39/98 - (39%)
• Gaps: 33/98 - (33%)

  Fly   161 DLRY-----NDRLTGSCLMSLPTSLLSLYITGCRNLCPNQLIFL---NRIPRLRELRASDLMP-- 215
            ||.|     :|:.||..       ||.|.::||..:..:.|..|   ..:|.|..|..|..:.
Human   583 DLIYFGSEKSDQETGRV-------LLFLSLSGCYQITDHGLRVLTLGGGLPYLEHLNLSGCLTIT 640

  Fly   216 -GGHWHIYRDLVLACPLLVMVEISICSLNRDEY 247
             .|    .:|||.|||          ||| |||
Human   641 GAG----LQDLVSACP----------SLN-DEY 658

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG15056	NP_573291.1	leucine-rich repeat	133..156	CDD:275381
		leucine-rich repeat	157..179	CDD:275381	6/22 (27%)
		leucine-rich repeat	180..204	CDD:275381	7/26 (27%)
		leucine-rich repeat	205..231	CDD:275381	9/28 (32%)
		leucine-rich repeat	232..285	CDD:275381	6/16 (38%)
		leucine-rich repeat	286..326	CDD:275381
		AMN1	306..>376	CDD:187754
		leucine-rich repeat	337..362	CDD:275381
FBXL5	NP_036293.1	Hemerythrin-like. /evidence=ECO:0000269|PubMed:19762596, ECO:0000269|PubMed:19762597	1..159
		Hr_FBXL5	7..160	CDD:213984
		F-box_FBXL5	205..245	CDD:438890
		leucine-rich repeat	332..357	CDD:275381
		LRR 1	340..364
		AMN1	354..>408	CDD:187754
		leucine-rich repeat	358..384	CDD:275381
		LRR 2	365..392
		leucine-rich repeat	385..435	CDD:275381
		LRR 3	393..418
		leucine-rich repeat	436..500	CDD:275381
		LRR 4	479..508
		leucine-rich repeat	501..537	CDD:275381
		leucine-rich repeat	538..583	CDD:275381	30/98 (31%)
		LRR 5	576..607		9/30 (30%)
		leucine-rich repeat	584..627	CDD:275381	12/49 (24%)
		AMN1	<603..>654	CDD:187754	16/64 (25%)
		LRR 6	608..635		6/26 (23%)
		leucine-rich repeat	628..653	CDD:275381	10/38 (26%)
		LRR 7	636..661		13/38 (34%)