DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG15056 and Fbxl19

DIOPT Version :9

Sequence 1:	NP_573291.1	Gene:	CG15056 / 32824	FlyBaseID:	FBgn0030918	Length:	399	Species:	Drosophila melanogaster
Sequence 2:	XP_036008913.1	Gene:	Fbxl19 / 233902	MGIID:	3039600	Length:	696	Species:	Mus musculus

Alignment Length:	228	Identity:	53/228 - (23%)
Similarity:	79/228 - (34%)	Gaps:	83/228 - (36%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 ISFSVISRFDFFW----LDVLKQLDLKSRISFAASCDMFENIYVRSSPLRLSRVVNLEEMIEFSL 64
            :|::.:|:....|    |..|::|.|       :.|.......:.|:||...|           |
Mouse   492 LSWTGVSKKQLMWLLNRLQGLQELVL-------SGCSWLSVSALGSAPLPALR-----------L 538

  Fly    65 LETKLFVELSGSDI-EIIRGGPHT-PMFSHFEDFIRLMSIRLTKVNEIALEGFQLTQYKWFNAPE 127
            |:.:...::..|.: |::...|.| |..:....       ||..|.|:.|.|.:||.
Mouse   539 LDLRWIEDVKDSQLRELLLPPPDTKPGQTESRG-------RLQGVAELRLAGLELTD-------- 588

  Fly   128 TSFSNLTYVSLRRCQLNDENLVGWEFLTH---LETLDLRYNDRLTGSC---------LMSLPTS- 179
                    .|||.            .|.|   |..|||.:       |         |::.|||
Mouse   589 --------ASLRL------------LLRHAPQLSALDLSH-------CAHVGDPSVHLLTAPTSP 626

  Fly   180 ----LLSLYITGCRNLCPNQLIFLNRIPRLREL 208
                |:.|.:.||..|..:.|....|.||||.|
Mouse   627 LRETLVHLNLAGCHRLTDHCLPLFRRCPRLRRL 659

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15056	NP_573291.1	leucine-rich repeat	133..156	CDD:275381	4/22 (18%)
		leucine-rich repeat	157..179	CDD:275381	7/30 (23%)
		leucine-rich repeat	180..204	CDD:275381	7/23 (30%)
		leucine-rich repeat	205..231	CDD:275381	3/4 (75%)
		leucine-rich repeat	232..285	CDD:275381
		leucine-rich repeat	286..326	CDD:275381
		AMN1	306..>376	CDD:187754
		leucine-rich repeat	337..362	CDD:275381
Fbxl19	XP_036008913.1	zf-CXXC	<52..79	CDD:366873
		PHD_FXL19	89..150	CDD:277115
		F-box-like	426..467	CDD:403981
		AMN1	468..667	CDD:187754	53/228 (23%)
		leucine-rich repeat	488..511	CDD:275381	4/18 (22%)
		leucine-rich repeat	512..535	CDD:275381	7/29 (24%)
		leucine-rich repeat	573..600	CDD:275381	12/54 (22%)
		leucine-rich repeat	601..627	CDD:275381	9/32 (28%)
		leucine-rich repeat	631..655	CDD:275381	7/23 (30%)
		leucine-rich repeat	656..680	CDD:275381	3/4 (75%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167843173
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1947
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.830