DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG15056 and fbxl13

DIOPT Version :9

Sequence 1:	NP_573291.1	Gene:	CG15056 / 32824	FlyBaseID:	FBgn0030918	Length:	399	Species:	Drosophila melanogaster
Sequence 2:	XP_017209779.1	Gene:	fbxl13 / 101883454	ZFINID:	ZDB-GENE-140106-120	Length:	796	Species:	Danio rerio

Alignment Length:	463	Identity:	106/463 - (22%)
Similarity:	168/463 - (36%)	Gaps:	110/463 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 ISFSVISRFDFFW---------LDVLKQLDLKSRISFAASCDMFENIYVRSSPLRLSRVVNLEEM 59
            :||..||.|.|.:         ::::|   :::...|...|...:.:.:...|     .||.|.|
Zfish   305 LSFRRISTFTFIYQTTAFIFCFVNLIK---IQNTFVFKGQCRNLQELDLSECP-----TVNDENM 361

  Fly    60 IEF-----SLLETKL-FVELSGSDIEIIRGGPHTPMFS-------HFED----FI-------RLM 100
            ...     |||...| ...::.:.|:::.......:.|       ||.|    ::       ||.
Zfish   362 KMILEGCQSLLSLNLACTHIANATIKVLASRCCVMLRSLNLAYCIHFSDKGLQYLTTGTGCRRLR 426

  Fly   101 SIRLTKVNEIALEGF--------QLTQYKWFNAPETSFSNLTYVSLRRCQ-------LNDENLVG 150
            .:.|:..::|.::||        .|.|....:.| |.......|.:.||:       |...||..
Zfish   427 HLNLSGCSQITVDGFTSVAETCNSLQQIVLNDLP-TLTDICVQVLVSRCRMLTVISLLESLNLSD 490

  Fly   151 WEFLTHLETLDL-----RYND--------------------------RLTGSCLMSLP--TSLLS 182
            ..|....|.:||     ..||                          |:|.:|..:|.  |.|.:
Zfish   491 VAFKAVAEVIDLTKILIEGNDVITDSSVKALCRSCLKLSELHLSCCPRVTDACFKTLGNLTKLCN 555

  Fly   183 LYITGCRNLCPNQLIFLNRIPRLRELRASDLMPGGHWHIYRDLVL-----ACPLLVMVEISICSL 242
            |.|:||..:....|.::...|...:||..||   .:.....||.|     .|..|..:.:..|.
Zfish   556 LNISGCFKVTDMGLHYITEGPSAGQLRELDL---SYCLKITDLSLRRISQKCISLTNLALCFCE- 616

  Fly   243 NRDEYRLGELRYLQSLVIKAHSTDTIRCKVSDWMLISLLDVPFLRNLMFSDAPSGFVSANALSII 307
            |..:.....|....||:    |.|...||:.|..|.:|...|.||.|  |.|...|::...:.:.
Zfish   617 NLTDNGFECLDKCSSLI----SLDISGCKIHDKGLSALGANPSLRKL--SAAECVFITDIGIKMF 675

  Fly   308 SRFRQLRVLKMPNQPYRPNDLLRLRNLTF----LETLDLSNSPYITNEVVIELVIGIPNLSVLIV 368
            .|..|...|....|..|.:| ..::.|:|    :.|:.::..|.:|:..|..|......|..|.|
Zfish   676 CRLCQRLELLDVCQCVRLSD-RAIKALSFFCRTIATVRIAGCPKMTDAAVKYLTRAGHFLRELDV 739

  Fly   369 QGCPLLTN 376
            .||.|||:
Zfish   740 SGCSLLTD 747

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15056	NP_573291.1	leucine-rich repeat	133..156	CDD:275381	7/29 (24%)
		leucine-rich repeat	157..179	CDD:275381	9/54 (17%)
		leucine-rich repeat	180..204	CDD:275381	6/23 (26%)
		leucine-rich repeat	205..231	CDD:275381	8/30 (27%)
		leucine-rich repeat	232..285	CDD:275381	13/52 (25%)
		leucine-rich repeat	286..326	CDD:275381	11/39 (28%)
		AMN1	306..>376	CDD:187754	20/73 (27%)
		leucine-rich repeat	337..362	CDD:275381	5/24 (21%)
fbxl13	XP_017209779.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170588096
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1947
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1282076at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.840