DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG15056 and si:ch73-236c18.7

DIOPT Version :9

Sequence 1:	NP_573291.1	Gene:	CG15056 / 32824	FlyBaseID:	FBgn0030918	Length:	399	Species:	Drosophila melanogaster
Sequence 2:	XP_021331546.1	Gene:	si:ch73-236c18.7 / 100333378	ZFINID:	ZDB-GENE-121214-3	Length:	1015	Species:	Danio rerio

Alignment Length:	411	Identity:	83/411 - (20%)
Similarity:	123/411 - (29%)	Gaps:	176/411 - (42%)

- Green bases have known domain annotations that are detailed below.

  Fly    18 DVLKQLDL---------KSRI---------SFAASCDM-FENIYVRSSPLRLSRVVNLEEMIEFS 63
            :||.:|:|         :.|:         :..|.|:: .::..:.||.|:.|..| |.|:
Zfish   677 EVLDELELQKYNTSDEGRRRLIPAVSNCTRALLAGCNLSAQDCEIVSSVLQSSNCV-LREL---- 736

  Fly    64 LLETKLFVELSGSDIEIIRGGPHTPMFSHFEDFIRLMSIRLTKVNEIALEGFQLTQYKWFNAPET 128
                    :||.:|::              :..::|:|..|...|
Zfish   737 --------DLSNNDLQ--------------DSGVKLLSDGLKSPN-------------------- 759

  Fly   129 SFSNLTYVSLRRCQLNDENLVGWEFL--------THLETLDLRYNDRLTG-SCLMSLPTSLLSLY 184
              ..|..:.|..|.:.:|   |..||        :||..|||.||.  .| |.:..|..:|...:
Zfish   760 --CQLEILRLSGCMVTEE---GCGFLSSALSSNPSHLRELDLSYNH--PGQSGVQLLQHTLEDPH 817

  Fly   185 ITGCRNLCPNQLIFLNR---IPRLRELRASDLMPGGHWHIYRDLVLACPLLVMVEISICSLNR-- 244
            .|    |...:|.|..|   ||.||:...             ||.|. |.....::.:...||
Zfish   818 YT----LQKLKLDFGGRSRIIPGLRKYAV-------------DLTLD-PNTANAQLQLSEGNRKA 864

  Fly   245 ------DEYRLGELRYLQSLVIKAHSTDTIRC-----------------------KVSD------ 274
                  .:|.....|:.....:....|.|.||                       .|||
Zfish   865 THVKDPQQYPDHPERFDTYPQVLCKETLTGRCYWEAEWNGRVTGIAVASRGISRKGVSDCVFGWN 929

  Fly   275 ---WML-----------------ISLLDVPFLRNLMFSDAPSGFVSANALSIISRFRQLRVLKMP 319
               |.|                 |:....|..|..:|.|.||||||..::|.......|...
Zfish   930 DKSWSLFCSDNSYVVCHNNDRTDITAPSPPSNRVGVFLDVPSGFVSFYSVSDTHTLTHLHTF--- 991

  Fly   320 NQPYRPNDLLRLRNLTFLETL 340
                         |.||.|.|
Zfish   992 -------------NTTFTEPL 999

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15056	NP_573291.1	leucine-rich repeat	133..156	CDD:275381	7/30 (23%)
		leucine-rich repeat	157..179	CDD:275381	9/22 (41%)
		leucine-rich repeat	180..204	CDD:275381	7/26 (27%)
		leucine-rich repeat	205..231	CDD:275381	5/25 (20%)
		leucine-rich repeat	232..285	CDD:275381	14/109 (13%)
		leucine-rich repeat	286..326	CDD:275381	11/39 (28%)
		AMN1	306..>376	CDD:187754	6/35 (17%)
		leucine-rich repeat	337..362	CDD:275381	2/4 (50%)
si:ch73-236c18.7	XP_021331546.1	COG5635	102..>606	CDD:227922
		FISNA	133..203	CDD:316956
		NACHT	212..379	CDD:310381
		LRR_RI	<660..825	CDD:330982	41/205 (20%)
		leucine-rich repeat	733..761	CDD:275378	9/75 (12%)
		leucine-rich repeat	762..790	CDD:275378	7/30 (23%)
		SPRY_PRY_SNTX	835..1012	CDD:294002	38/195 (19%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1282076at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.010