DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG32549 and Nt5dc2

DIOPT Version :9

Sequence 1:	NP_728163.2	Gene:	CG32549 / 32822	FlyBaseID:	FBgn0052549	Length:	709	Species:	Drosophila melanogaster
Sequence 2:	NP_001361016.1	Gene:	Nt5dc2 / 70021	MGIID:	1917271	Length:	553	Species:	Mus musculus

Alignment Length:	607	Identity:	168/607 - (27%)
Similarity:	273/607 - (44%)	Gaps:	113/607 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    42 SRRLSLKSGEI-PKHGQGSQTAPSRIYPIHIGA--PNCQRSRRNKG---NRRLSCSYASLGRMQA 100
            :|||.|..|.. |:....|.:.|. ..|...||  |:..||....|   :..|...|..:.|:
Mouse    10 ARRLLLCRGHSGPRAASSSPSCPG-CGPPGPGAHCPSTPRSAPADGADLSAHLWARYQDMRRL-- 71

  Fly   101 TPSEDAQPQDPLKSFERDFCDLPPYQCEMSDSAPNTPGPCSTSALPKKYYRYAAHRVFVNRSLHL 165
                           ..|.  |||..|.:.:.|                      .::.|..:.|
Mouse    72 ---------------VHDL--LPPEVCSLLNPA----------------------AIYANNEISL 97

  Fly   166 ENIKYYGFDMDYTLAEYKSPQYEQLGFNLVKERLV-FMGYPKEILQFEYDPTFPVRGLWFDTLYG 229
            .:::.||||.|||||:|....:.:: ||..::.|: ...||:.|.:::|||:|.:|||.:|....
Mouse    98 SDVEVYGFDYDYTLAQYADALHPEI-FNAARDILIEHYKYPEGIRKYDYDPSFAIRGLHYDIQKS 161

  Fly   230 NLLKVDA--YGNILVCVHGFEFIKHHQVYELYPNKFLKLDESRVYVLN-------------TLFN 279
            .|:|:||  |..:.....|.:.:...:|.:||..    .....:|.::             .:|:
Mouse   162 LLMKIDAFHYVQLGTAYRGLKPVPDDEVIDLYGG----TQHIPLYQMSGFYGKGPSIKQFMDIFS 222

  Fly   280 LPETYLLACLVD-FLTNSSDFVRVERGIKAGDLLFTYKSIFQDVRRAVDWVHSDGDLKRRTTQNM 343
            |||..||:|:|| ||.:..:|.:|.              :::||..|:..||..|.:.:...|:|
Mouse   223 LPEMALLSCVVDYFLGHGLEFDQVH--------------LYKDVTDAIRDVHVKGLMYQWIEQDM 273

  Fly   344 AHYVKKDERLPTVLSRIRESGAKLFMLTNSDYTYTNEIMTYLFDFPHGATPDEPHRDWKTYFDVI 408
            ..|:.:.:....||||:...|.:||::|||.:::.::.|.      |...|     ||:..|||:
Mouse   274 EKYILRGDETFAVLSRLVAHGKQLFLITNSPFSFVDKGMR------HMVGP-----DWRQLFDVV 327

  Fly   409 VVDARKPLFF-DEGTVLRQVDTKTGSLKIGTHVGPLQPGQVYSGGSCELFTKFINAKGKDVLYVG 472
            :|.|.||.|| |.....|::|.| |||. ...:..|:.|::|..|:...|.:....:|..|||.|
Mouse   328 IVQADKPNFFTDRRKPFRKLDEK-GSLH-WDRITRLEKGKIYRQGNLFDFLRLTEWRGPRVLYFG 390

  Fly   473 DHIFGDILKSKKIRGWRTFLIVPELVRELHVWTDECQLFA-----ELQNLDIKLGDLYRDLDSS- 531
            ||::.|:.......||||..|:|||.||:.:...|..:.:     .|..| ::....|:|.:|.
Mouse   391 DHLYSDLADLMLRHGWRTGAIIPELEREIRIINTEQYMHSLTWQQALTGL-LERMQTYQDAESRQ 454

  Fly   532 --AKVKPDISQLRTCIRDVTHKMDMSYGMMGSLFRSGSRQTFFSSQVVRYADVYAATLLNLIYYP 594
              |....:..:|| ||...     :.....||:||:....|:||.::||::|:|.|:|..|:.|.
Mouse   455 VLATWMKERQELR-CITKA-----LFNAQFGSIFRTFHNPTYFSRRLVRFSDLYMASLSCLLNYR 513

  Fly   595 FSYMFRAPAMLLPHESTVAHDQ 616
            ..:.|......|.||:.:..||
Mouse   514 VDFTFYPRRTPLQHEAPLWMDQ 535

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32549	NP_728163.2	5_nucleotid	165..610	CDD:283430	140/470 (30%)
Nt5dc2	NP_001361016.1	5_nucleotid	97..530	CDD:377556	141/471 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167843196
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.840