Protein Alignment Nt5b and Nt5dc2

DIOPT Version :10

• Sequence 1: NP_728163.2
• Gene: Nt5b / 32822
• FlyBaseID: FBgn0052549
• Length: 709
• Species: Drosophila melanogaster
• Sequence 2: NP_001361016.1
• Gene: Nt5dc2 / 70021
• MGIID: 1917271
• Length: 553
• Species: Mus musculus
• Alignment Length: 607
• Identity: 168/607 - (27%)
• Similarity: 273/607 - (44%)
• Gaps: 113/607 - (18%)

  Fly    42 SRRLSLKSGEI-PKHGQGSQTAPSRIYPIHIGA--PNCQRSRRNKG---NRRLSCSYASLGRMQA 100
            :|||.|..|.. |:....|.:.|. ..|...||  |:..||....|   :..|...|..:.|:
Mouse    10 ARRLLLCRGHSGPRAASSSPSCPG-CGPPGPGAHCPSTPRSAPADGADLSAHLWARYQDMRRL-- 71

  Fly   101 TPSEDAQPQDPLKSFERDFCDLPPYQCEMSDSAPNTPGPCSTSALPKKYYRYAAHRVFVNRSLHL 165
                           ..|.  |||..|.:.:.|                      .::.|..:.|
Mouse    72 ---------------VHDL--LPPEVCSLLNPA----------------------AIYANNEISL 97

  Fly   166 ENIKYYGFDMDYTLAEYKSPQYEQLGFNLVKERLV-FMGYPKEILQFEYDPTFPVRGLWFDTLYG 229
            .:::.||||.|||||:|....:.:: ||..::.|: ...||:.|.:::|||:|.:|||.:|....
Mouse    98 SDVEVYGFDYDYTLAQYADALHPEI-FNAARDILIEHYKYPEGIRKYDYDPSFAIRGLHYDIQKS 161

  Fly   230 NLLKVDA--YGNILVCVHGFEFIKHHQVYELYPNKFLKLDESRVYVLN-------------TLFN 279
            .|:|:||  |..:.....|.:.:...:|.:||..    .....:|.::             .:|:
Mouse   162 LLMKIDAFHYVQLGTAYRGLKPVPDDEVIDLYGG----TQHIPLYQMSGFYGKGPSIKQFMDIFS 222

  Fly   280 LPETYLLACLVD-FLTNSSDFVRVERGIKAGDLLFTYKSIFQDVRRAVDWVHSDGDLKRRTTQNM 343
            |||..||:|:|| ||.:..:|.:|.              :::||..|:..||..|.:.:...|:|
Mouse   223 LPEMALLSCVVDYFLGHGLEFDQVH--------------LYKDVTDAIRDVHVKGLMYQWIEQDM 273

  Fly   344 AHYVKKDERLPTVLSRIRESGAKLFMLTNSDYTYTNEIMTYLFDFPHGATPDEPHRDWKTYFDVI 408
            ..|:.:.:....||||:...|.:||::|||.:::.::.|.      |...|     ||:..|||:
Mouse   274 EKYILRGDETFAVLSRLVAHGKQLFLITNSPFSFVDKGMR------HMVGP-----DWRQLFDVV 327

  Fly   409 VVDARKPLFF-DEGTVLRQVDTKTGSLKIGTHVGPLQPGQVYSGGSCELFTKFINAKGKDVLYVG 472
            :|.|.||.|| |.....|::|.| |||. ...:..|:.|::|..|:...|.:....:|..|||.|
Mouse   328 IVQADKPNFFTDRRKPFRKLDEK-GSLH-WDRITRLEKGKIYRQGNLFDFLRLTEWRGPRVLYFG 390

  Fly   473 DHIFGDILKSKKIRGWRTFLIVPELVRELHVWTDECQLFA-----ELQNLDIKLGDLYRDLDSS- 531
            ||::.|:.......||||..|:|||.||:.:...|..:.:     .|..| ::....|:|.:|.
Mouse   391 DHLYSDLADLMLRHGWRTGAIIPELEREIRIINTEQYMHSLTWQQALTGL-LERMQTYQDAESRQ 454

  Fly   532 --AKVKPDISQLRTCIRDVTHKMDMSYGMMGSLFRSGSRQTFFSSQVVRYADVYAATLLNLIYYP 594
              |....:..:|| ||...     :.....||:||:....|:||.::||::|:|.|:|..|:.|.
Mouse   455 VLATWMKERQELR-CITKA-----LFNAQFGSIFRTFHNPTYFSRRLVRFSDLYMASLSCLLNYR 513

  Fly   595 FSYMFRAPAMLLPHESTVAHDQ 616
            ..:.|......|.||:.:..||
Mouse   514 VDFTFYPRRTPLQHEAPLWMDQ 535

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nt5b	NP_728163.2	5_nucleotid	165..611	CDD:461733	141/471 (30%)
Nt5dc2	NP_001361016.1	5_nucleotid	97..530	CDD:461733	141/471 (30%)