Protein Alignment Nt5b and Nt5dc1

DIOPT Version :10

• Sequence 1: NP_728163.2
• Gene: Nt5b / 32822
• FlyBaseID: FBgn0052549
• Length: 709
• Species: Drosophila melanogaster
• Sequence 2: NP_001099863.2
• Gene: Nt5dc1 / 294456
• RGDID: 1305214
• Length: 461
• Species: Rattus norvegicus
• Alignment Length: 485
• Identity: 115/485 - (23%)
• Similarity: 190/485 - (39%)
• Gaps: 127/485 - (26%)

  Fly   172 GFDMDYTLAEYKSPQYEQLGFN-----LVKERLVFMGYPKEILQFEY-DPTFPVRGLWFDTLYGN 230
            |||:|:||..|...:...|.:|     ||||:    ||.:|:|.... |..|..:||..|...|.
  Rat    14 GFDLDHTLCRYNLSESAALIYNSFAQFLVKEK----GYDEELLTLTLEDWDFCCKGLALDLEDGT 74

  Fly   231 LLKVDAYGNILVCVHGFEFIKHHQVYELYPNKFLK--LDESR-------------VYVLNTLFNL 280
            .:|:.|.|.:|...||.:.:....:.|.|..|..:  |.:.|             .|..:..|:|
  Rat    75 FIKLAADGTVLRASHGTKMMTPEALTEAYGKKEWRHCLSDKRSVSGSDIPCCSGKCYFYDNYFDL 139

  Fly   281 PETYLLACLVDFLTNSS------DFVR-VERGIKAGDLLFTYKS----IFQDVRRAVDWVHSDGD 334
            |...|.|.:||.||..:      ||.: |..||:....:..:|.    .|.:::|
  Rat   140 PGALLCAKVVDSLTKQNRGQKTFDFWKDVVAGIQHNFKMSAFKENCGFFFPEIKR---------- 194

  Fly   335 LKRRTTQNMAHYVKK-DERLPTVLSRIRESGAKLFMLTNSDYTYTNEIMTYLFDFPHGATPDEPH 398
                   |:..||.: .|.:...|.:|:::|....::|:|...|...:.:|:..
  Rat   195 -------NLGKYVYRCPESVKKWLQQIKDAGKITMLITSSHSDYCKLLGSYILG----------- 241

  Fly   399 RDWKTYFDVIVVDARKPLFF---------------DEGTVLRQVDTKTGSLKIGTHVGPLQPGQV 448
            :|:...||:::.:|.||.||               :|...|..:|               :||.
  Rat   242 KDFADLFDIVITNALKPGFFSHFPSQRSFYTLENDEEKDELPSLD---------------KPGW- 290

  Fly   449 YSGGSC----ELFTKFINAKGKDVLYVGDHIFGDILKSKKIRGWRTFLIVPELVRELHVWTDECQ 509
            ||.|:.    ||..|..:.....|:|.||.:..||..:.....|.|.||:.||..:      |.:
  Rat   291 YSQGNAVHLYELLKKMTSKLEPKVVYFGDSMHSDIFPAHHYTNWETVLILEELQGQ------EME 349

  Fly   510 LFAELQNLDIKLGDLYRDLDSSAKVKPDISQLRTCIRDVTHKMDMSYGMMGSLFRSGSRQ----- 569
            ...|.:.|: |.|..     ...||||        :..:::|.. || .:.|:.|.|:.:
  Rat   350 KPEEAEPLE-KRGKY-----EGPKVKP--------LNCLSNKWG-SY-FIDSVSRRGNAEDSLVY 398

  Fly   570 TFFSSQVVRYADVYAATLLNLIYYPFSYMF 599
            |:.|.::..|:.:....:.::...|..|.|
  Rat   399 TWSSKRISTYSTIAIPNIESIAELPLDYKF 428

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nt5b	NP_728163.2	5_nucleotid	165..611	CDD:461733	115/485 (24%)
Nt5dc1	NP_001099863.2	Haloacid Dehalogenase-like Hydrolases	3..343	CDD:473868	92/376 (24%)