Protein Alignment Tsf1 and tf

DIOPT Version :10

• Sequence 1: NP_523401.2
• Gene: Tsf1 / 32821
• FlyBaseID: FBgn0022355
• Length: 641
• Species: Drosophila melanogaster
• Sequence 2: NP_001027487.1
• Gene: tf / 613079
• XenbaseID: XB-GENE-480506
• Length: 703
• Species: Xenopus tropicalis
• Alignment Length: 759
• Identity: 172/759 - (22%)
• Similarity: 286/759 - (37%)
• Gaps: 202/759 - (26%)

  Fly     8 HTWLPLAVAALLLILGPQSSLAEEPIYRLCV-PQIYLAECQQLLADPSEAGIRMECVAGRDRVDC 71
            |..|.|.:.||.|.:.|     :|...|.|. .:...::|:.|:.......|.:.||......:|
 Frog     6 HVALCLGMLALCLAMPP-----KEKQVRWCAKSKSEFSKCRDLVNTCKNKEITLSCVEKSSTDEC 65

  Fly    72 LELIEQRKADVLATEPEDMYIA----YHRK---NEDYRVISEIRTQQDKDAAFRYEGIILVKKDS 129
            |..|:..:||.:..:..|:|..    |:.|   .|:|...:|..|        .|..:.:|||.|
 Frog    66 LTAIQNDRADAICVDGGDVYKGSLQPYNLKPIMAENYGSHTEPDT--------CYYAVAVVKKSS 122

  Fly   130 PIRTLQQLRGAKSCHTGFGRNVGYKIPITKLKNTHVLKVSADPQISATERELKSLSEFFTQSCLV 194
            .. |..:||..:|||||.|:..|:.:.|..|....:||... |...:.|   |::|:||..||:.
 Frog   123 TF-TFDELRDKRSCHTGIGKTAGWNVIIGLLLEKQLLKWEG-PDTESLE---KAVSKFFKASCVP 182

  Fly   195 GTYSTHPETDRLLKKKYANLCALC--EKPEQC----NYPDKFSGYDGAIRCLDKGQGEVAFSKVQ 253
            |.             |...||..|  :|..:|    |.|  :..|.||.:||...:|:|||.|..
 Frog   183 GA-------------KEPKLCQQCAGKKEHKCARSNNEP--YYNYAGAFKCLQDDKGDVAFVKHS 232

  Fly   254 YIKKYFGLPGAGPDAPPAEGNPENFEYLCEDGTRRPVTG-PACSWAQRPWSGYISNEQAVHNSEQ 317
            .:              |.|.: :::|.||.|.||:|::. ..|:.|:.|....::..:...:.:.
 Frog   233 TV--------------PEELH-KDYELLCPDNTRKPISDYKNCNLAKVPAHSVLARARDDKSKDI 282

  Fly   318 LHQLQSRLE----RFFA--NGLQAQNKDAAAHLLIQP---------NAVYHSKDAAIDPKVYLER 367
            :..||...:    :.|:  :|.....||.|..|:..|         .|||:.       :::..:
 Frog   283 IAFLQEAQKTKECKLFSSQHGKDLLFKDTAVSLVPLPPTIDGFLFLGAVYYQ-------EIHALK 340

  Fly   368 AGYKDVIERDGSAIRKIRLCAQNDDEFAKCQALHQAAYARDARPELECVQST---DCVVALTKKE 429
            .|.|   |.|.:|..|:|.|.|:..|..||.     .:...:...:||.::.   ||::.:.|.:
 Frog   341 EGVK---EDDLAAPSKVRWCTQSKAEKTKCD-----DWTTISGGSIECTEAATAEDCILQILKGD 397

  Fly   430 ADLTIVRATGYADARSNQLQPIVYEQRAQDDV---------------LVAVAAPG---------- 469
            ||...:.......|....|.|::.|....||:               .||:|..|
 Frog   398 ADAVTLDGGYMYTAGQCGLVPVMGEYYDLDDLTPCQRRSSQAKGVYYAVAIAKKGTKVSWKNLRG 462

  Fly   470 --------------------VTRE-------------ALQKASIKFN----------------EN 485
                                :|.|             ....:.:|.|                :.
 Frog   463 VKTCHTAVGRTAGWNIPVGLITNETNNCDFASYVGESCAPGSDVKSNLCKLCIGDPAKPLDSAKK 527

  Fly   486 CERSRAAAALLNKRRGLDACRVSSSD-------------DGEVQIVPASELEKHKDAQLVCPSLE 537
            |  |.:|:...:...|...|.|...|             ||:.....|.:| |..|.:|:||...
 Frog   528 C--SPSASEAYHGYSGAFRCLVEKGDVCFAKHTTVFENTDGKNPAAWAKDL-KSDDYELLCPDGS 589

  Fly   538 RRPVTDFRDCNVDVQLPRAIFIRSDTTSVEQETVKHLFSLISDKFGARGKLVDVFALFGEFQKGK 602
            |.|:.||:.||: .::|....:   |...:::.|..:.......:|.:|...|:|.:|.  .|..
 Frog   590 RAPINDFKRCNL-AEVPAHSVV---TLPGKRKPVVEILVNQQSLYGRKGFQKDIFQMFQ--SKDG 648

  Fly   603 KNVYFNDKAVQLTTELK-----NEIQNEQIYTDL----QCNANK 637
            |::.|.| :.|...|:.     .|...::.||.:    :|:..|
 Frog   649 KDLLFKD-STQCLLEISEKTTMQEFLGDKYYTAVTSLNKCSNTK 691

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsf1	NP_523401.2	TR_FER	34..323	CDD:214514	79/303 (26%)
		Periplasmic_Binding_Protein_Type_2	384..615	CDD:473866	62/320 (19%)
tf	NP_001027487.1	PBP2_transferrin_N	26..340	CDD:270336	90/363 (25%)
		Connecting region. /evidence=ECO:0000250	341..350		4/11 (36%)
		PBP2_transferrin_C	353..685	CDD:270335	67/346 (19%)