DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Tsf1 and otomp

DIOPT Version :9

Sequence 1:	NP_001285404.1	Gene:	Tsf1 / 32821	FlyBaseID:	FBgn0022355	Length:	641	Species:	Drosophila melanogaster
Sequence 2:	NP_001038552.1	Gene:	otomp / 565818	ZFINID:	ZDB-GENE-040709-1	Length:	371	Species:	Danio rerio

Alignment Length:	335	Identity:	82/335 - (24%)
Similarity:	139/335 - (41%)	Gaps:	42/335 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 LAVAALLLILGPQSSLAEEPIYRLC-VPQIYLAECQQLLADPSEAGIR--MECVAGRDRVDCLEL 74
            |||...|.:|...|:  |..|.|.| |......:|..|..:.:...:|  :.||.|:...||::.
Zfish     8 LAVVLFLFVLVSMST--ENNIIRWCTVSDAEDQKCLDLAGNATARNLRGQLVCVRGQSPTDCMKQ 70

  Fly    75 IEQRKADVLATEPEDMYIAYH------RKNEDYRVISEIRTQQDKDAAFRYEGIILVKKDSPIRT 133
            |:...||......:::|.|..      ...|.|..:..|          .|..:.|.:..|...:
Zfish    71 IKNGTADASTMYADEIYTAGFCYGLDVAVGESYNGVDGI----------NYYVVALARTSSSDLS 125

  Fly   134 LQQLRGAKSCHTGFGRNVGYKIPITKLKNTHVLKVSADPQISATERELKSLSEFFTQSCLVGTYS 198
            |.::....|||.|....||:.:||..|.||.  ::|.|.|.:...    ::.:||..||:.|.
Zfish   126 LLEMHERSSCHPGMRTTVGWTVPIGFLVNTS--QISVDVQCNFPH----AVGDFFGYSCVPGV-- 182

  Fly   199 THPETDRLLKKKYANLCALCEKPEQ-----CNYP-DKFSGYDGAIRCLDKGQGEVAFSKVQYIKK 257
            ..||.|. ......|||..|...|.     .|.| ::..|..||:||:.:..|:|||  |::...
Zfish   183 KDPEHDP-KGNNPRNLCEACIGDENDRHICANNPRERHFGEAGALRCVAENLGDVAF--VKHTTV 244

  Fly   258 YFGLPGAGPDAPPAEGNPENFEYLCEDGTRRPV-TGPACSWAQRPWSGYISNEQAVHNSEQLHQL 321
            :..:.|...::...:...|:.:.||.||:...: ...:|..|..|.:..:..   :.:..::::.
Zfish   245 FDNMQGKNQESWALDLELEDLKLLCPDGSEANLFQHESCHLAVVPTNAVVVR---LEDKCRVYKF 306

  Fly   322 QSRLERFFAN 331
            ..|::..|.|
Zfish   307 LERVQNAFGN 316

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Tsf1	NP_001285404.1	PBP2_transferrin	34..>302	CDD:270247	70/283 (25%)
		Periplasmic_Binding_Protein_Type_2	384..615	CDD:304360
		TR_FER	384..614	CDD:214514
otomp	NP_001038552.1	TR_FER	27..363	CDD:214514	74/314 (24%)
otomp	NP_001038552.1	PBP2_transferrin	27..363	CDD:270247	74/314 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_28KI0
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D125278at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	4	3.780