Protein Alignment Tsf1 and tfa

DIOPT Version :9

• Sequence 1: NP_001285404.1
• Gene: Tsf1 / 32821
• FlyBaseID: FBgn0022355
• Length: 641
• Species: Drosophila melanogaster
• Sequence 2: NP_001278428.1
• Gene: tfa / 30255
• ZFINID: ZDB-GENE-980526-35
• Length: 673
• Species: Danio rerio
• Alignment Length: 728
• Identity: 159/728 - (21%)
• Similarity: 280/728 - (38%)
• Gaps: 191/728 - (26%)

  Fly    11 LPLAVAALLLILGPQSSLAEEPIYRLCVPQIYLAECQQLLADPSEAGIRMECVAGRDRVDCLELI 75
            |.:::...|::..|.:| |::.:......|...::|:.|....::    :||......:||:..|
Zfish     4 LLISLLGCLVVALPSAS-AQKKVKWCVTTQNEQSKCRHLATKAAD----IECHLQPTVIDCMRSI 63

  Fly    76 EQRKADVLATEPEDMYIAYHRKNEDYRVISEIRTQQDKDAAFRYEGIILVKKDSPIRTLQQLRGA 140
            .....|::..:..:::..    ..:..::..|..::.|:..:   .:..||..|.. .:.:|:|.
Zfish    64 AAGGTDIVTVDGANVFTG----GLNNYLLRPIIAEKKKECCY---AVAAVKAGSGF-NINELKGK 120

  Fly   141 KSCHTGFGRNVGYKIPITKLKNTHVLKVSAD-PQISATERELKSLSEFFTQSCLVGTYSTHPETD 204
            .|||:.:.|:.|:..||.||..|:  |::.: |.....||   ::||||:.||:.|
Zfish   121 SSCHSCYQRSGGWNTPIGKLIATN--KITWEGPNEMPVER---AVSEFFSSSCVPG--------- 171

  Fly   205 RLLKKKYANLCALCEKPEQCNYPDKFSGYDGAIRCLDKGQGEVAFSKVQYIKKYFGLPGAGPDAP 269
             :.|.||.|||..|:....|::.:|:.|.|||.:||....|:|||      ..:..:|
Zfish   172 -VSKPKYPNLCKACQGDCSCSHNEKYFGDDGAFQCLKNDNGQVAF------VCHHAIP------- 222

  Fly   270 PAEGNPENFEYLCEDGTRRPVTG-PACSWAQRPWSGYISNEQAVHNSEQLHQLQSRLERFFANGL 333
              |...:|:|.||.||:|:.|.. ..|::|:.|....|:     .....|..:...|::..|:.|
Zfish   223 --ESERQNYELLCMDGSRKSVEDYKTCNFAREPARTVIA-----RTDTDLQYVYDVLKQIPASDL 280

  Fly   334 QAQN---------KDAAAHLLIQPNAVYHSKDAAIDPKVYLERAGYKDV-IERDG-----SAIRK 383
            .:..         .|:|..|::.|...        |..:||:...|:.: ..:||     ::..|
Zfish   281 FSSQAFGGKDLIFSDSATELMLLPKRT--------DSLLYLKEEYYEAMQAFKDGNPSAPTSQTK 337

  Fly   384 IRLCAQNDDEFAKCQALHQAAYARDARPELECVQST---DCVVALTKKEADLTIVRATGYADARS 445
            :.:|.....|..||.:|...        :..|:...   ||:..:.:||||...|.......|..
Zfish   338 LAMCTIGHAEKNKCDSLDHV--------KKSCILEASVDDCIEKIKRKEADFLAVDGGQVYIAGK 394

  Fly   446 NQLQPIVYEQRAQDD-------------VLVAVAAPGVTREALQ--------------------- 476
            ..|.|::.||.....             |.|.....|:|...|:
Zfish   395 CGLVPVMAEQSNSQSCSSGSGGTASYYAVAVVRKGSGLTWNNLEGKKSCHTGLGRSAGWKIPESA 459

  Fly   477 ------KASIK--FNENC----------------------ERSRAAAALLNKRRGLD-ACRVSSS 510
                  |.::.  |:|.|                      :.|:...:...:..|.| |.|..:.
Zfish   460 ICGEKDKCTLDKFFSEGCAPGADPTSNMCKLCKGSGKPVGDESKCKPSAEEQYYGYDGAFRCLAE 524

  Fly   511 DDGEVQIVP---------------ASELEKHKDAQLVCPSLERRPV--TDFRDCNVDVQLP-RAI 557
            ..|:|..:.               |.:| |.:|.:|:||:.....:  |||..||: .|:| .|:
Zfish   525 KAGDVAFIKHTVVGDYTDGKGKDWAKDL-KSEDFELICPNTPDTTMKYTDFEKCNL-AQVPVHAV 587

  Fly   558 FIRSDTTSVEQETVKHLFSLISDKFGARGKLVDVFALFGEFQKGKKNVYFND--KAVQLTTELKN 620
            ..|.|..|.       :.|.:||   .:.|..|:|.     .|..||:.|.|  |.:|   |:|.
Zfish   588 ITREDARSA-------VVSFLSD---IQSKNNDLFT-----SKDGKNLLFTDGTKCLQ---EIKG 634

  Fly   621 EIQN--EQIYTDL 631
            .:.:  .:.|.|:
Zfish   635 SVDDFLTKKYIDM 647

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsf1	NP_001285404.1	PBP2_transferrin	34..>302	CDD:270247	68/269 (25%)
		Periplasmic_Binding_Protein_Type_2	384..615	CDD:304360	65/318 (20%)
		TR_FER	384..614	CDD:214514	64/317 (20%)
tfa	NP_001278428.1	Periplasmic_Binding_Protein_Type_2	25..325	CDD:304360	82/354 (23%)
		TR_FER	25..322	CDD:214514	82/351 (23%)
		Periplasmic_Binding_Protein_Type_2	336..648	CDD:304360	70/340 (21%)
		TR_FER	341..653	CDD:214514	69/335 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D125278at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11485
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	3.020