Protein Alignment Tsf1 and Tf

DIOPT Version :10

• Sequence 1: NP_523401.2
• Gene: Tsf1 / 32821
• FlyBaseID: FBgn0022355
• Length: 641
• Species: Drosophila melanogaster
• Sequence 2: NP_001013128.1
• Gene: Tf / 24825
• RGDID: 3845
• Length: 698
• Species: Rattus norvegicus
• Alignment Length: 722
• Identity: 174/722 - (24%)
• Similarity: 270/722 - (37%)
• Gaps: 191/722 - (26%)

  Fly    13 LAVAALLLILGPQSSLAEEPIYRLCVPQIYLAEC--------QQLLADPSEAGIRMECVAGRDRV 69
            ||.|||.|.|    ::.::.:....|.:....:|        ..|.||    |.|:.||......
  Rat     9 LACAALGLCL----AVPDKTVKWCAVSEHENTKCISFRDHMKTVLPAD----GPRLACVKKTSYQ 65

  Fly    70 DCLELIEQRKADVLATEPEDMYIAYHRKNEDYRVISEIRTQQDKDAAFRYEGIILVKKDSPIRTL 134
            ||::.|...:||.:..:...:|.|....|....|.:|.....:.... .|..:.:|||.:..: |
  Rat    66 DCIKAISGGEADAITLDGGWVYDAGLTPNNLKPVAAEFYGSLEHPQT-HYLAVAVVKKGTDFQ-L 128

  Fly   135 QQLRGAKSCHTGFGRNVGYKIPITKLKNTHVLKVSADPQISATEREL-KSLSEFFTQSCLVGTYS 198
            .||:|.||||||.||:.|:.|||..|          ...:....:.| |:::.||:.||:
  Rat   129 NQLQGKKSCHTGLGRSAGWIIPIGLL----------FCNLPEPRKPLEKAVASFFSGSCV----- 178

  Fly   199 THPETDRLLKKKYANLCALCEKPEQCNYPDKFSGYDGAIRCLDKGQGEVAFSKVQYIKKYFGLPG 263
              |..|.:...:...||..|    .|:....|.||.||.:||..|.|:|||.|...|.:..
  Rat   179 --PCADPVAFPQLCQLCPGC----GCSPTQPFFGYVGAFKCLRDGGGDVAFVKHTTIFEVL---- 233

  Fly   264 AGPDAPPAEGNPENFEYLCEDGTRRPVTG-PACSWAQRPWSGYISNEQAVHNSEQLHQL------ 321
                  |.:.:.:.:|.||.|.||:||.. ..|..|:.|     |:.....|.:....|
  Rat   234 ------PQKADRDQYELLCLDNTRKPVDQYEDCYLARIP-----SHAVVARNGDGKEDLIWEILK 287

  Fly   322 ---------QSRLERFFAN--GLQAQNKDAAAHLLIQPNAVYHSKDAAIDPKVYLERAGYKDVI- 374
                     :|:..:.|.:  |.....||:|..||..|        ..:|.::||..: |...|
  Rat   288 VAQEHFGKGKSKDFQLFGSPLGKDLLFKDSAFGLLRVP--------PRMDYRLYLGHS-YVTAIR 343

  Fly   375 -ERDG--------SAIRKIRLCAQNDDEFAKCQALHQAAYARDARPELECVQST-DCVVALTKKE 429
             :|:|        ||  .::.||.:..|.|||.   :.:.:.:.:.|.|..:|| ||:..:...|
  Rat   344 NQREGVCPEGSIDSA--PVKWCALSHQERAKCD---EWSVSSNGQIECESAESTEDCIDKIVNGE 403

  Fly   430 AD-LTIVRATGYADARSNQLQPIVYEQ-------RAQDDVL----VAVAAPGVTREALQKASIKF 482
            || :::.....|...:.. |.|::.|.       ..|.||.    .|||....:..::...::|.
  Rat   404 ADAMSLDGGHAYIAGQCG-LVPVMAENYDISSCTNPQSDVFPKGYYAVAVVKASDSSINWNNLKG 467

  Fly   483 NENCER--SRAAA-----ALL---------------------------------------NKRRG 501
            .::|..  .|.|.     .||                                       |.|.|
  Rat   468 KKSCHTGVDRTAGWNIPMGLLFSRINHCKFDEFFSQGCAPGYKKNSTLCDLCIGPAKCAPNNREG 532

  Fly   502 LDA------CRVSSSD-------------DGEVQIVPASELEKHKDAQLVCPSLERRPVTDFRDC 547
            .:.      |.|...|             :|:.....|.:| |.:|.||:||...::|||:|..|
  Rat   533 YNGYTGAFQCLVEKGDVAFVKHQTVLENTNGKNTAAWAKDL-KQEDFQLLCPDGTKKPVTEFATC 596

  Fly   548 NVDVQLPRAIFIRSDTTSVEQETV----KHLFSLISDKFGARGKLVDVFALFGEFQKGKKNVYFN 608
            :: .|.|..:.:.....:....||    |.|| ...||        |....|..|:...|::.|.
  Rat   597 HL-AQAPNHVVVSRKEKAARVSTVLTAQKDLF-WKGDK--------DCTGNFCLFRSSTKDLLFR 651

  Fly   609 DKAVQLT 615
            |....||
  Rat   652 DDTKCLT 658

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsf1	NP_523401.2	TR_FER	34..323	CDD:214514	81/313 (26%)
		Periplasmic_Binding_Protein_Type_2	384..615	CDD:473866	66/312 (21%)
Tf	NP_001013128.1	PBP2_transferrin_N	24..346	CDD:270336	95/372 (26%)
		PBP2_transferrin_C	357..682	CDD:270335	70/319 (22%)