Protein Alignment Tsf1 and Ltf

DIOPT Version :10

• Sequence 1: NP_523401.2
• Gene: Tsf1 / 32821
• FlyBaseID: FBgn0022355
• Length: 641
• Species: Drosophila melanogaster
• Sequence 2: NP_032548.2
• Gene: Ltf / 17002
• MGIID: 96837
• Length: 707
• Species: Mus musculus
• Alignment Length: 723
• Identity: 175/723 - (24%)
• Similarity: 283/723 - (39%)
• Gaps: 214/723 - (29%)

  Fly    57 GIRMECVAGRDRVDCLELIEQRKADVLATEPEDMYIAYHRKNEDYRVISEIRTQQDKDAAFRYEG 121
            |..:.||.......|::.|...:||.:..:...|:.|.....:...|.:|:...:::... .|..
Mouse    49 GPPLSCVKKSSTRQCIQAIVTNRADAMTLDGGTMFDAGKPPYKLRPVAAEVYGTKEQPRT-HYYA 112

  Fly   122 IILVKKDSPIRTLQQLRGAKSCHTGFGRNVGYKIPITKLK---NTHVLKVSADPQISATERELKS 183
            :.:||..|... |.||:|.:|||||.||:.|:||||..|:   |.:      .|..|..|    :
Mouse   113 VAVVKNSSNFH-LNQLQGLRSCHTGIGRSAGWKIPIGTLRPYLNWN------GPPASLEE----A 166

  Fly   184 LSEFFTQSCLVGTYSTHPETDRLLKKKYANLCALC---------EKPEQCNYPDKFSGYDGAIRC 239
            :|:||::||:.|..          |.::.|||:.|         ..||     :.:|||.||:||
Mouse   167 VSKFFSKSCVPGAQ----------KDRFPNLCSSCAGTGANKCASSPE-----EPYSGYAGALRC 216

  Fly   240 LDKGQGEVAFSKVQYIKKYFGLPGAGPDAPPAEGNPENFEYLCEDGTRRPVTG-PACSWAQRPWS 303
            |....|:|||::...:.:..          |.:...:.::.||.|.|.:|||. ..|..||.|..
Mouse   217 LRDNAGDVAFTRGSTVFEEL----------PNKAERDQYKLLCPDNTWKPVTEYKECHLAQVPSH 271

  Fly   304 GYIS-----NEQAVHNSEQLHQLQSRLERFFANGLQ-----AQNKDAAAHLLIQPNAV-YHSKDA 357
            ..:|     .|:|:.  |.|.|.|.:..:..|:|.|     :..||    ||.:.:|: :.....
Mouse   272 AVVSRSTNDKEEAIW--ELLRQSQEKFGKKQASGFQLFASPSGQKD----LLFKESAIGFVRVPQ 330

  Fly   358 AIDPKVYLE----------RAGYKDVIERDGSAIRKIRLCAQNDDEFAKCQALHQAAYARDARPE 412
            .:|..:||.          ....:|||    ::..::..||...:|..||...::|     :|..
Mouse   331 KVDVGLYLTFSYTTSIQNLNKKQQDVI----ASKARVTWCAVGSEEKRKCDQWNRA-----SRGR 386

  Fly   413 LECVQ---STDCVVALTKKEAD----------------LTIVRATGYADARSNQL----QPIVYE 454
            :.|:.   :.||:||:.|.:||                |..|.|.....::||.|    :|:
Mouse   387 VTCISFPTTEDCIVAIMKGDADAMSLDGGYIYTAGKCGLVPVLAENQKSSKSNGLDCVNRPV--- 448

  Fly   455 QRAQDDVLVAVAAPGVTRE--------------------------------ALQKASIKFNE--- 484
                 :..:||||  |.||                                |.|..|.||||
Mouse   449 -----EGYLAVAA--VRREDAGFTWSSLRGKKSCHTAVDRTAGWNIPMGLLANQTRSCKFNEFFS 506

  Fly   485 -NC-----ERSRAAAALLNKRRGLDACRVSSSD---------------DGEVQIVPASEL----- 523
             :|     .:|...|..:...:|.:.|..:|.:               .|.|..:..|.:
Mouse   507 QSCAPGADPKSNLCALCIGDEKGENKCAPNSKERYQGYTGALRCLAEKAGNVAFLKDSTVLQNTD 571

  Fly   524 ----------EKHKDAQLVCPSLERRPVTDFRDCNVDVQLPRAIFIRSDTTSVEQETVKHLFSLI 578
                      .|.||.:|:|....|:|||:.::|::.:....|:..|:|...|.|:.      |:
Mouse   572 GKNTEEWARNLKLKDFELLCLDDTRKPVTEAKNCHLAIAPNHAVVSRTDKVEVLQQV------LL 630

  Fly   579 SD--KFGARGKLVDVFALFGE---FQKGKKNVYFNDKAVQL------TTELKNEIQNEQIYTD-- 630
            ..  :||..|:...     ||   ||...||:.|||....|      ||..|...:...|.|:
Mouse   631 DQQVQFGRNGQRCP-----GEFCLFQSKTKNLLFNDNTECLAKIPGKTTSEKYLGKEYVIATERL 690

  Fly   631 LQCNANKI 638
            .||:::.:
Mouse   691 KQCSSSPL 698

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsf1	NP_523401.2	TR_FER	34..323	CDD:214514	79/283 (28%)
		Periplasmic_Binding_Protein_Type_2	384..615	CDD:473866	74/335 (22%)
Ltf	NP_032548.2	Transferrin	24..351	CDD:395328	91/344 (26%)
		PBP2_transferrin_C	361..691	CDD:270335	79/355 (22%)