DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment betaCOP and AT5G11490

DIOPT Version :9

Sequence 1:	NP_523400.1	Gene:	betaCOP / 32820	FlyBaseID:	FBgn0008635	Length:	964	Species:	Drosophila melanogaster
Sequence 2:	NP_001190290.1	Gene:	AT5G11490 / 831021	AraportID:	AT5G11490	Length:	850	Species:	Arabidopsis thaliana

Alignment Length:	798	Identity:	156/798 - (19%)
Similarity:	278/798 - (34%)	Gaps:	214/798 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    36 KIETLKRVIKLLLNGERYPGL----------IMTIIRFVLPVQNHTIKKLLLIFWEIVPKTSADG 90
            ::..||..::.|. |.|.||:          :::.:...:.|.:        :|.|:|..::...
plant    21 EVSDLKTQLRQLA-GSRAPGVDDSKRDLYKKVISYMTIGIDVSS--------VFGEMVMCSATSD 76

  Fly    91 KLLQEM----------------ILVCDAYRKDLQHPNEFLRGSTLRFLCKLKEPELLEPLMPAIR 139
            .:|::|                :|..:..::|.:..:..:||..||.||.|:.|.|:|.|:..:.
plant    77 IVLKKMCYLYVGNYAKGNPDLSLLTINFLQRDCKDEDPMIRGLALRSLCSLRVPNLVEYLVGPLG 141

  Fly   140 ACLDHRHSYVRRNAVLAIFTIYKNFDWLVP------DGPELIASFLDTQQDMSCKRNAFLMLLHA 198
            :.|...:||||..||..:..:|.    :.|      |.|..:.|.:....|.....|....|...
plant   142 SGLKDNNSYVRTIAVTGVLKLYH----ISPSTCIDADFPATLKSLMLHDSDAQVVANCLSALQEI 202

  Fly   199 DQERALNYLASC---------------IDQVHTFGDILQLVIVELIYKVCHANPAERSRFIRCIY 248
            ....|.:...:|               ::::..|.:..|.:|:||..|..   |:: |..|..|.
plant   203 WSLEASHSEEACREKESLLSKPVIYYFLNRIKEFNEWAQCLILELAVKYV---PSD-SNDIFDIM 263

  Fly   249 NLLNSSSNAVRYESAGTLITLSLAPTAIKAAASCYIELVVKESD------NNVKLIVLDRLVAMK 307
            |||..     |.:.|...:.|        |....:::|.:..:|      ..:|..:| .||:..
plant   264 NLLED-----RLQHANGAVVL--------ATVKVFLQLTLSMTDVHQQVYERIKSPLL-TLVSSG 314

  Fly   308 EHEGMEKVMQDLVMDVLRV--LAAPDIE-----------VRRKTLALALDLVYSRNIGEMVLVLK 359
            ..|....::..|.:.|:|.  :.|.|.:           |::..|.:...:....|..|:|..|.
plant   315 SPEQSYAILSHLHLLVVRAPFIFAADYKHFYCQYNEPSYVKKLKLEMLTAVANESNTYEIVTELC 379

  Fly   360 KEVAKTHNVEHEDTGKYRQLLVRTLHTCSIKFPDVAANVIPVLVEFLSDTNELAAADVLIFIREA 424
            :..|   ||   |....|: .:|.:...:::..||.| ::..|::||....:...|:.|:.:::.
plant   380 EYAA---NV---DIAIARE-SIRAVGKIALQQYDVNA-IVDRLLQFLEMEKDYVTAETLVLVKDL 436

  Fly   425 IQKFPALRALIIEHLIEAFPQIKSSKIHR-----AAVWILGEYVEGSQILEVIAVIQQTLGEVPM 484
            ::|:|...    ...|.....|.|..|..     |.:|:||||.             |.:.:.|.
plant   437 LRKYPQWS----HDCISVVGGISSKNIQEPKAKAALIWMLGEYA-------------QDMSDAPY 484

  Fly   485 VEAEQRRLAGDQTEEQKQQQGSAGGNAAGSAAEGSGSGNASNKVTSDGTYATQSAYSLAPVAKA- 548
            |   ...|..:..||..                                 |....:.|....|.
plant   485 V---LENLIENWEEEHS---------------------------------AEVRLHLLTAAMKCF 513

  Fly   549 EKRPPLRQYLMDGDFFIGAALSATLT--------KLALRYAELETEARAQNRLTTQVMLIMSSIL 605
            .||.|..|..      :|.||:|.:.        :....|..|:.:.....|:.:.....:|...
plant   514 FKRAPETQKA------LGTALAAGIADFHQDVHDRALFYYRVLQYDVHVAERVVSPPKQAVSVFA 572

  Fly   606 HLGKSGFPSKPITNDDTDRIFVCLRTLSERTPEAISVFTLYCREALGKMLDAQHDEDQRMLKEKQ 670
            ....|         :..||:|....:||....:...:||           |.:|........|..
plant   573 DTQSS---------EIKDRVFDEFNSLSVIYQKPSYMFT-----------DKEHRGPFEFSDEVG 617

  Fly   671 KATAKVQPDDPVLFAQL--SNGRDNQLG-----ENVFESSLN------QALAGSKN--AQLSDVA 720
            ..:...:....::.||.  :|.:|..||     ||...|:.|      .:|..|.|  :|:.::|
plant   618 NISITPEASSDIVPAQQYEANDKDLLLGIDEKDENKGVSNNNGSAYTAPSLESSSNITSQMQELA 682

  Fly   721 SPNSKLNKVT-QLTGFSD 737
            ......:..| |..||.|
plant   683 ISGPATSATTPQSFGFDD 700

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
betaCOP	NP_523400.1	Adaptin_N	17..562	CDD:279882	117/597 (20%)
		Coatamer_beta_C	678..820	CDD:285019	20/76 (26%)
		Coatomer_b_Cpla	826..953	CDD:291472
AT5G11490	NP_001190290.1	Adaptin_N	41..551	CDD:279882	115/606 (19%)
		HEAT repeat	101..129	CDD:293787	8/27 (30%)
		Cnd1	113..288	CDD:289487	45/195 (23%)
		HEAT repeat	135..165	CDD:293787	9/33 (27%)
		HEAT repeat	174..201	CDD:293787	6/26 (23%)
		B2-adapt-app_C	727..836	CDD:198088
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5096
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810