Protein Alignment betaCOP and sec26

DIOPT Version :10

• Sequence 1: NP_523400.1
• Gene: betaCOP / 32820
• FlyBaseID: FBgn0008635
• Length: 964
• Species: Drosophila melanogaster
• Sequence 2: NP_595403.1
• Gene: sec26 / 2539798
• PomBaseID: SPBC146.14C
• Length: 940
• Species: Schizosaccharomyces pombe
• Alignment Length: 961
• Identity: 388/961 - (40%)
• Similarity: 610/961 - (63%)
• Gaps: 43/961 - (4%)

  Fly     7 CYTIINSPDLEVTNEMQLKRDLEKGDTNVKIETLKRVIKLLLNGERYPGLIMTIIRFVLPVQNHT 71
            |:|::....||..:...||..||..:..|||..:|.::::::||:..|.::|.:||||:|.:|..
pombe     3 CWTLVQQDFLEAPSVDALKTSLESKNDYVKISAMKTILRVVINGDSLPSILMHVIRFVMPSRNKE 67

  Fly    72 IKKLLLIFWEIVPKTSADGKLLQEMILVCDAYRKDLQHPNEFLRGSTLRFLCKLKEPELLEPLMP 136
            :||||..:||:.||.:.||.:.|||||.|:::|.||||||||:||:||||||||||||||:||:|
pombe    68 LKKLLYYYWEVCPKYNNDGTMKQEMILACNSFRNDLQHPNEFIRGATLRFLCKLKEPELLDPLIP 132

  Fly   137 AIRACLDHRHSYVRRNAVLAIFTIYKNFDWLVPDGPELIASFLDTQQDMSCKRNAFLMLLHADQE 201
            .:|.||:|||:|||:||:||:|:||:..:.|:||...|...||..:.:.:|||||.::|...|.|
pombe   133 TVRQCLEHRHAYVRKNAILAVFSIYQVSNHLIPDAASLAEDFLAAESEGTCKRNALIVLFTIDPE 197

  Fly   202 RALNYLASCIDQVHTFGDILQLVIVELIYKV--CHANPAERSRFIRCIYNLLNSSSNAVRYESAG 264
            :|..:|.:..:|:.:......|||:|.|.||  ..|:..|:.||...:.:|..:::::|.:|:|.
pombe   198 KAKAWLLANFEQIPSLNASSLLVIIEFIRKVVLTKADGLEKLRFQSLLVSLTATNNSSVVFEAAT 262

  Fly   265 TLITLSLAPTAIKAAASCYIELVVKESDNNVKLIVLDRLVAMKEHEGMEKVMQDLVMDVLRVLAA 329
            ::|.:.....::|.|||..:.|..:|:|||.|||:|||:..:...:  :.:::||:.||:..|::
pombe   263 SVINVFPDAESLKLAASRLLALADREADNNAKLIMLDRISQLAARD--KSILEDLITDVIPFLSS 325

  Fly   330 PDIEVRRKTLALALDLVYSRNIGEMVLVLKKEVAKTHNVEHEDTGKYRQLLVRTLHTCSIKFPDV 394
            .|.:|..|.:::.:.||.|||:.:::...:||:.|::....:|.|: |:.|.:.:|:|:|.||..
pombe   326 SDFDVCEKAISIIMGLVSSRNVEDILNHFQKELTKSNGETEKDDGR-RRALTKAIHSCAINFPHT 389

  Fly   395 AANVIPVLVEFLSDTNELAAADVLIFIREAIQKFPALRALIIEHLIEAFPQIKSSKIHRAAVWIL 459
            ||..|..|:..:||....:|:.||.||:|.::|||.||:..|..|:.:..::::.||.|..:||.
pombe   390 AATAIQYLLSHISDFQSKSASSVLSFIKEVMEKFPDLRSSNITKLLLSLKELRAGKIFRGVIWIA 454

  Fly   460 GEYVEGSQILEVI-AVIQQTLGEVPMVEAEQRRL--AGDQTEEQKQQQGSAGGNAAGSAAEGSGS 521
            |||......:.|. ..|:.:|||||::.:|::.|  ..:..|:.             ...:.|..
pombe   455 GEYCLTEDDIRVAWKSIRASLGEVPILASEEQLLKDVSNVPEDD-------------LLIDISAP 506

  Fly   522 GNASNKVTSDGTYATQSAYSLAPVA-------KAEKRPPLRQYLMDGDFFIGAALSATLTKLALR 579
            .:.|.||..||||||:||.:...::       ||.|:||||..::.||:::.|.|::.||||.:|
pombe   507 ASTSRKVLPDGTYATESAVTSEALSAARLEAVKASKKPPLRTQILSGDYYLAAVLASALTKLVMR 571

  Fly   580 YAELETEARAQNRLTTQVMLIMSSILHLGKSGFPSKPITNDDTDRIFVCLRTL--SERTPEAISV 642
            :|.|..:....|.|..:..|||:||:.:|:|.|....|.:|..:||..|:|.:  .|..||..:|
pombe   572 FARLSFDKERLNALKAEACLIMTSIIRVGQSKFVKYTIDDDSVERIMNCIRAIYSFEELPEFQTV 636

  Fly   643 FTLYCREALGKMLDAQHDEDQRMLKEKQKATAKVQPDDPVLFAQLSNGRDNQLGENVFESSLNQA 707
            |....|:|...:: ||.|:.|:........:..||.|:.:...|.....:.:...| |||.:.||
pombe   637 FLDDMRKAFSSLV-AQSDKRQKEADLLVNGSDAVQADELLNIRQFQRVIEEKQDLN-FESDIIQA 699

  Fly   708 LAGSKNAQLSDVASPNSKLNKVTQLTGFSDPVYAEAYVNVNQYDIVLDVLIVNQTNDTLQNCTLE 772
            .  :....:.|:|   |||:.:.||.||:||||.||||.:.|:||:||:|:||:|:.||||.:::
pombe   700 T--NDGMVVEDLA---SKLDHIVQLAGFTDPVYCEAYVKIQQFDIILDILLVNRTDTTLQNLSVD 759

  Fly   773 LATLGDLKLVERPHPVVLAPHDFCNIKANVKVSSTENGIIFGNIVY--ETALNTNVVVLNTIHID 835
            ||||||||:||||.|:.|.||.|.:::|.|||||||:.:|||||||  :.:....:||||.|.::
pombe   760 LATLGDLKVVERPPPMNLGPHAFKSVQATVKVSSTESAVIFGNIVYGGKASDEDKIVVLNGIPVN 824

  Fly   836 IMDYIIPASCTDTEFRQMWQDFEWENKVTVNTS-FTDLHEYLKHLLKSTNMKCLTPEKALSGQCG 899
            |:|||.||...:::||.||.:|||||||.:::: ...|:::|..::|.|||.||||:.:|.|.||
pombe   825 IIDYIKPAFIPESQFRSMWTEFEWENKVDISSNEDISLYDFLHKIMKKTNMNCLTPDASLRGDCG 889

  Fly   900 FMAANMYAKSIFGENALANLSIEKPVDDPDSKVTGHIRIRAKSQGMALSLG 950
            |::||:||.|||||:||.:||:||.|..|   ::||:|||:|:||:|||||
pombe   890 FLSANLYACSIFGEDALMSLSVEKSVSGP---ISGHVRIRSKTQGIALSLG 937

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
betaCOP	NP_523400.1	Adaptin_N	17..562	CDD:396262	208/556 (37%)
		Coatamer_beta_C	678..819	CDD:462245	70/142 (49%)
		Coatomer_b_Cpla	825..953	CDD:434227	67/127 (53%)
sec26	NP_595403.1	COG5096	1..923	CDD:227427	376/945 (40%)