| Sequence 1: | NP_523400.1 | Gene: | betaCOP / 32820 | FlyBaseID: | FBgn0008635 | Length: | 964 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_001240781.1 | Gene: | AP4B1 / 10717 | HGNCID: | 572 | Length: | 739 | Species: | Homo sapiens |
| Alignment Length: | 541 | Identity: | 108/541 - (19%) |
|---|---|---|---|
| Similarity: | 196/541 - (36%) | Gaps: | 154/541 - (28%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 26 RDLEKGDTNVKIE--------TLKRVIKLLLNGERYPGLIMTIIRFVLPVQNHTIKKLLLIFWEI 82
Fly 83 VPKTSADGKLLQEMILVCDAYRKDLQHPNEFLRGSTLRFLCKLKEPELLEPLMPAIRACLDHRHS 147
Fly 148 YVRRNAVLAIFTIYKNFDWLVPDGP---ELIASFLDTQQD----MSCKRNAFLMLLHADQERAL- 204
Fly 205 ------NYLASCIDQVHTFGDILQLVIVELIYKVCHANPAERSRFIRCIYNLLNSSSNAVRYESA 263
Fly 264 GTLITLSLAPTAIKAAASCYIELVVKESDNNVKLIVLDRLVAMKEHEGMEKVMQDLVMDVLRVLA 328
Fly 329 APDIEVRRKTLALALDLVYSRNIGEMVLVLKKEVAKTHNVEHEDTGKYRQLLVRTLHTCSIKFPD 393
Fly 394 -VAANVIPVLVEFLSDTN-----------------ELAAADVL-------IFIREAIQKFPALRA 433
Fly 434 LIIEHL----IEAF-------PQ---------------IKSSKIHRAAVWILGEYVEGSQILEVI 472
Fly 473 AVIQQTLGEV-----PMVEAE 488 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| betaCOP | NP_523400.1 | Adaptin_N | 17..562 | CDD:279882 | 108/541 (20%) |
| Coatamer_beta_C | 678..820 | CDD:285019 | |||
| Coatomer_b_Cpla | 826..953 | CDD:291472 | |||
| AP4B1 | NP_001240781.1 | Adaptin_N | 9..525 | CDD:331138 | 108/541 (20%) |
| HEAT repeat | 86..113 | CDD:293787 | 10/30 (33%) | ||
| HEAT repeat | 120..150 | CDD:293787 | 10/29 (34%) | ||
| HEAT repeat | 159..185 | CDD:293787 | 7/27 (26%) | ||
| HEAT repeat | 198..222 | CDD:293787 | 3/29 (10%) | ||
| Hinge. /evidence=ECO:0000305|PubMed:26542808 | 534..600 | ||||
| Ear, mediates interaction with TEPSIN. /evidence=ECO:0000269|PubMed:26542808 | 601..739 | ||||
| B2-adapt-app_C | 621..730 | CDD:312560 | |||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 1 | 0.900 | - | - | E1_COG5096 | |
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 2 | 1.810 | |||||