Protein Alignment por and PORCN

DIOPT Version :10

• Sequence 1: NP_476890.1
• Gene: por / 32818
• FlyBaseID: FBgn0004957
• Length: 525
• Species: Drosophila melanogaster
• Sequence 2: XP_047298313.1
• Gene: PORCN / 64840
• HGNCID: 17652
• Length: 574
• Species: Homo sapiens
• Alignment Length: 491
• Identity: 155/491 - (31%)
• Similarity: 238/491 - (48%)
• Gaps: 82/491 - (16%)

  Fly    72 LQSCVQPSVLQVMQYVAPMLLLCLLCRLLCLL----YSQRRRLTSLAPLHLFHFACGLIILQITV 132
            ||.|:.|:..|.:..:..:|.:||.||||..|    |.:.....:.....|:||      .|:
Human   127 LQGCLLPTAQQGLDQIWLLLAICLACRLLWRLGLPSYLKHASTVAGGFFSLYHF------FQL-- 183

  Fly   133 GYRLLLLLLLAAVGYLLLQLLR-LGRRG----AQVLAVLTVGSQFLYELLIWRRRSDWPQLRGIQ 192
              .::.::||:.:.||:|.|.| ...||    ..:|..|.:|...:.:.:.|.:      :||.|
Human   184 --HMVWVVLLSLLCYLVLFLCRHSSHRGVFLSVTILIYLLMGEMHMVDTVTWHK------MRGAQ 240

  Fly   193 MVVNMKLISLGFDLTASGQLQARIPGPFAYLGYIYSPATCALGPWVSFGCYMDCLVPRN---SWL 254
            |:|.||.:||||||. .|:: ..:|.|..::||:|...|...|||:||..|:..:..|.   .||
Human   241 MIVAMKAVSLGFDLD-RGEV-GTVPSPVEFMGYLYFVGTIVFGPWISFHSYLQAVQGRPLSCRWL 303

  Fly   255 VSLRRLLPNVVICVLAVTVSNCVAPALSDFF-----------------GDSSHFLVMYWDALSVR 302
            ..:.|.|...::|::   :|.||.|.|..:|                 |....:|..|..|:|..
Human   304 QKVARSLALALLCLV---LSTCVGPYLFPYFIPLNGDRLLRNKKRKARGTMVRWLRAYESAVSFH 365

  Fly   303 SSHYFVGMMAQALLVASDQRLDGATKESDML--GPLISQPWRIEWPRSISSLVRSWNIPMHEWLK 365
            .|:||||.:::|....:..   |.|:|.|.|  ...:|:|..:|.|||:..:|.|||:||..||.
Human   366 FSNYFVGFLSEATATLAGA---GFTEEKDHLEWDLTVSKPLNVELPRSMVEVVTSWNLPMSYWLN 427

  Fly   366 RYIYAPCKPTASTSRGRILVVVLSTYLVSSLLHGMDLRIYLVLISLAFLAEGESLLRRQLASLLN 430
            .|::.......:.|      .||.||..|:||||....:..||:||||:...|.:||::||.:|:
Human   428 NYVFKNALRLGTFS------AVLVTYAASALLHGFSFHLAAVLLSLAFITYVEHVLRKRLARILS 486

  Fly   431 ACITANLCPGKERCRYSHCPSKRRLNSLSYWLARLTNLAFTALAIFHLAYLGVVLLGDDLEVGED 495
            ||:.:..||       ..|..:.|| .|.   .|..||.|.|||||||||||.:.   |::|.:.
Human   487 ACVLSKRCP-------PDCSHQHRL-GLG---VRALNLLFGALAIFHLAYLGSLF---DVDVDDT 537

  Fly   496 ------GDSFLWH-WQQAGYLSHYIGLGTFVLYLFI 524
                  |.::..| |.:..:.||::..|.::.|..|
Human   538 TEEQGYGMAYTVHKWSELSWASHWVTFGCWIFYRLI 573

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
por	NP_476890.1	MBOAT	161..459	CDD:427117	102/319 (32%)
PORCN	XP_047298313.1	MBOAT	138..>456	CDD:445070	104/347 (30%)