Protein Alignment CrebB and ATF1

DIOPT Version :10

• Sequence 1: NP_001334685.1
• Gene: CrebB / 32817
• FlyBaseID: FBgn0265784
• Length: 331
• Species: Drosophila melanogaster
• Sequence 2: XP_047284834.1
• Gene: ATF1 / 466
• HGNCID: 783
• Length: 305
• Species: Homo sapiens
• Alignment Length: 331
• Identity: 101/331 - (30%)
• Similarity: 128/331 - (38%)
• Gaps: 121/331 - (36%)

  Fly    75 VSSVLTTTANCNIQYPIQTLAQHGLQVQSVIQANPSGVIQTAAGTQQQQQALAAATAMQKVVYVA 139
            :..|.....:.|...|:..:...|.|||  ||    ||||||
Human    11 IEFVFVLLMSLNGSAPVTIIRLPGEQVQ--IQ----GVIQTA----------------------- 46

  Fly   140 KPPNSTVIHTTPGNAVQVRNKIPPTFPCKIKPEPNTQHPEDSDESLSDDDSQHHRSELTRRPSYN 204
               .|:|||......:|       .|...:.....::..:||.:|:......|  ..|.|||||.
Human    47 ---QSSVIHPPHVQMIQ-------KFEDLVSSLSESEESQDSSDSIGSSQKAH--GILARRPSYR 99

  Fly   205 KIFTEISGPDM---------SGASL--------------------------------PMSDGVLN 228
            ||..::|..|.         ||.|.                                |.:|||..
Human   100 KILKDLSSEDTRGRKGDGENSGVSAAVTSMSVPTPIYQTSSGQYIAIAPNGALQLASPGTDGVQG 164

  Fly   229 SQ-LAGTGAGGNAANSSLMQ----------LDP--------------TYYLSNRMSYN------- 261
            .| |..|.:|.....::::|          |.|              ||.:....|..
Human   165 LQTLTMTNSGSTQQGTTILQYAQTSDGQQILVPSNQVVVQTASGDMQTYQIRTTPSATSLPQTVV 229

  Fly   262 -------TNNSGIAEDQTRKREIRLQKNREAARECRRKKKEYIKCLENRVAVLENQNKALIEELK 319
                   |:.:...:|...||||||.||||||||||||||||:|||||||||||||||.||||||
Human   230 MTSPVTLTSQTTKTDDPQLKREIRLMKNREAARECRRKKKEYVKCLENRVAVLENQNKTLIEELK 294

  Fly   320 SLKELY 325
            :||:||
Human   295 TLKDLY 300

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CrebB	NP_001334685.1	pKID	<191..>214	CDD:396650	10/22 (45%)
		bZIP_CREB1	274..327	CDD:269838	47/52 (90%)
		coiled coil	275..327	CDD:269838	46/51 (90%)
ATF1	XP_047284834.1	pKID	82..116	CDD:396650	11/35 (31%)
		bZIP_CREB1	249..303	CDD:269838	47/52 (90%)
		coiled coil	250..302	CDD:269838	46/51 (90%)