Protein Alignment CrebB and Atf6

DIOPT Version :10

• Sequence 1: NP_001334685.1
• Gene: CrebB / 32817
• FlyBaseID: FBgn0265784
• Length: 331
• Species: Drosophila melanogaster
• Sequence 2: NP_001100666.1
• Gene: Atf6 / 304962
• RGDID: 1305471
• Length: 656
• Species: Rattus norvegicus
• Alignment Length: 240
• Identity: 54/240 - (22%)
• Similarity: 91/240 - (37%)
• Gaps: 58/240 - (24%)

  Fly    96 QHGLQVQSVIQANPSGVIQTAAGTQQQQQALAAATAMQKVVYVAKPPNSTVIHTTPGNAVQVRNK 160
            :|||        .|...||.::....|.:.|....|.:.....:.|..:.:|.|
  Rat   149 EHGL--------TPKKKIQMSSKPSVQPKPLLLPAAPKTPANASVPAKTIIIQT----------- 194

  Fly   161 IPPTFP-------CKIKPEPNTQHPEDSDESLSDDDSQHHRSELTRRPSYNKIFTEISGPD---- 214
            :|...|       ..|:|.|.                 ..::.|..:|:..::.|....|.
  Rat   195 LPALMPLAKQQSIISIQPAPT-----------------KGQTVLLSQPAVVQLQTPGVLPSAQPV 242

  Fly   215 --MSGASLPMSDGVLNSQLAGTGAGGNAANSSLMQLDPTYYLSNRMSYNTNNSGIAEDQTRKREI 277
              ::|.:..:.:.|:|  :.......:..|..|....|....|.|    :..|.||   ..:|:.
  Rat   243 LAVTGGATQLPNHVVN--VVPAPVVNSPVNGKLCVTKPVLQSSTR----STGSDIA---VLRRQQ 298

  Fly   278 RLQKNREAARECRRKKKEYIKCLENRVAVLENQNKALIEELKSLK 322
            |:.||||:|.:.|:|||||:..||.|:....::|:.|.:|..|||
  Rat   299 RMIKNRESACQSRKKKKEYMLGLEARLKAALSENEQLKKENGSLK 343

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CrebB	NP_001334685.1	pKID	<191..>214	CDD:396650	3/22 (14%)
		bZIP_CREB1	274..327	CDD:269838	22/49 (45%)
		coiled coil	275..327	CDD:269838	22/48 (46%)
Atf6	NP_001100666.1	Transcription activation. /evidence=ECO:0000305	1..137
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	81..171		7/29 (24%)
		Basic motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU00978	295..326		16/30 (53%)
		bZIP_ATF6	296..347	CDD:269848	22/48 (46%)
		coiled coil	296..347	CDD:269848	22/48 (46%)
		Leucine-zipper. /evidence=ECO:0000255|PROSITE-ProRule:PRU00978	335..342		2/6 (33%)
		Interaction with THBS4. /evidence=ECO:0000250|UniProtKB:P18850	455..575
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	632..656