DRSC/TRiP Functional Genomics Resources

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Protein Alignment CrebB and FOS

DIOPT Version :9

Sequence 1:NP_001334685.1 Gene:CrebB / 32817 FlyBaseID:FBgn0265784 Length:331 Species:Drosophila melanogaster
Sequence 2:NP_005243.1 Gene:FOS / 2353 HGNCID:3796 Length:380 Species:Homo sapiens


Alignment Length:118 Identity:27/118 - (22%)
Similarity:48/118 - (40%) Gaps:23/118 - (19%)


- Green bases have known domain annotations that are detailed below.


  Fly   208 TEISGPDMSGASLPMSDGVLNSQLAGTGAGGNAAN----SSLMQLDPTYYLSNRMSYNTNNSGIA 268
            ::...|...|...|.:.....:.:..|..||.|.:    ..:.||.|                  
Human    88 SQTRAPHPFGVPAPSAGAYSRAGVVKTMTGGRAQSIGRRGKVEQLSP------------------ 134

  Fly   269 EDQTRKREIRLQKNREAARECRRKKKEYIKCLENRVAVLENQNKALIEELKSL 321
             ::..||.||.::|:.||.:||.:::|....|:.....||::..||..|:.:|
Human   135 -EEEEKRRIRRERNKMAAAKCRNRRRELTDTLQAETDQLEDEKSALQTEIANL 186

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CrebBNP_001334685.1 None
FOSNP_005243.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 119..138 4/37 (11%)
Basic motif, required for the activation of phospholipid synthesis, but not for CDS1-binding 139..159 9/19 (47%)
bZIP_Fos 147..200 CDD:269869 13/40 (33%)
coiled coil 147..199 CDD:269869 13/40 (33%)
Leucine-zipper. /evidence=ECO:0000255|PROSITE-ProRule:PRU00978 165..193 7/22 (32%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 354..380
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 1 1.030 - avgDist Average_Evolutionary_Distance R103
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.940

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