DRSC/TRiP Functional Genomics Resources

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Protein Alignment CrebB and Atf7

DIOPT Version :9

Sequence 1:NP_001334685.1 Gene:CrebB / 32817 FlyBaseID:FBgn0265784 Length:331 Species:Drosophila melanogaster
Sequence 2:NP_001296995.1 Gene:Atf7 / 223922 MGIID:2443472 Length:483 Species:Mus musculus


Alignment Length:314 Identity:66/314 - (21%)
Similarity:101/314 - (32%) Gaps:107/314 - (34%)


- Green bases have known domain annotations that are detailed below.


  Fly    45 GGNPQQQQQNPQSTTAGGPTGATNNAQGGGVSSVLTTTANCNIQYPIQTLAQHGLQVQSVIQANP 109
            |..|.....:|...|...||            ||:|.....|.|.                 .:|
Mouse   154 GSLPLHLGYDPLHPTLPSPT------------SVITQAPPSNRQI-----------------GSP 189

  Fly   110 SG---VIQTAAGTQQQQQALAAATAMQKVVYVAKP----PNSTVIHTTPGNAVQVRNKIPPTFPC 167
            :|   ::...|..|...........|..|:.:|:|    ||   |...||..|.....|.|    
Mouse   190 TGSLPLVMHLANGQTMPMLPGPPVQMPSVISLARPVSMVPN---IPGIPGPPVNNSGSISP---- 247

  Fly   168 KIKPEPNTQHPEDSDESLSDDDSQHHR----------------SELTRRPSYNKIFTEISGPDMS 216
                   :.||..|:..:....:..|:                :.:|.||..|:|.  |..||..
Mouse   248 -------SGHPMPSEAKMRLKATLTHQVSSINGGCGMVVGTASTMVTARPEQNQIL--IQHPDAP 303

  Fly   217 GASLPMSDGVLNSQLAGTGAGGNAANSSLMQLDPTYYLSNRMSYNTNNSG------IAEDQTRKR 275
            ..:.|                         |:.|        :..|.::|      :.||...:|
Mouse   304 SPAQP-------------------------QVSP--------AQPTPSTGGRRRRTVDEDPDERR 335

  Fly   276 EIRLQKNREAARECRRKKKEYIKCLENRVAVLENQNKALIEELKSLKELYCQTK 329
            :..|::||.||..||:|:|.::..||.:...|.:||..|..|:..|:....|.|
Mouse   336 QRFLERNRAAASRCRQKRKLWVSSLEKKAEELTSQNIQLSNEVTLLRNEVAQLK 389

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CrebBNP_001334685.1 None
Atf7NP_001296995.1 Transactivation domain. /evidence=ECO:0000250 1..285 31/173 (18%)
C2H2 Zn finger 9..31 CDD:275370
GCN4_cent 47..84 CDD:213399
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 81..140
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 299..337 10/70 (14%)
bZIP_ATF2 334..394 CDD:269835 20/56 (36%)
coiled coil 334..394 CDD:269835 20/56 (36%)
Basic motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU00978 334..354 9/19 (47%)
Leucine-zipper. /evidence=ECO:0000255|PROSITE-ProRule:PRU00978 360..388 8/27 (30%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 1 1.030 - avgDist Average_Evolutionary_Distance R103
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.940

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