DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CrebB and Creb3l3

DIOPT Version :9

Sequence 1:	NP_001334685.1	Gene:	CrebB / 32817	FlyBaseID:	FBgn0265784	Length:	331	Species:	Drosophila melanogaster
Sequence 2:	NP_001369747.1	Gene:	Creb3l3 / 208677	MGIID:	2384786	Length:	479	Species:	Mus musculus

Alignment Length:	232	Identity:	65/232 - (28%)
Similarity:	93/232 - (40%)	Gaps:	68/232 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly   141 PPNSTVIHTTPGNAV-------QVRNKIP---PTFPCKIKPE-PNTQHPEDS---DESLSDDDSQ 191
            ||.|   .|.|.|.|       |.:...|   |:.||   || |.||..|.|   |..:...|:.
Mouse   102 PPRS---GTEPANTVARCHTREQGKGPCPSYLPSTPC---PEPPRTQVQESSVAIDLDMWSTDTL 160

  Fly   192 HHRSELTRRPSYNKIFTEISGPDMSGASLPMSD-GVLNSQLAGTGAGG------NAANSSLM--- 246
            :..........:|....|:.   :||.|..:.. .:..|||.|.|:|.      ......|:
Mouse   161 YPEEPAGSPSRFNLTVKELL---LSGGSGDLQQHSLAASQLLGPGSGHCQELVLTEDEKKLLAKE 222

  Fly   247 ------QLDPTYYLSNRMSYNTNNSGIAEDQTRKREIRLQKNREAARECRRKKKEYIKCLENRVA 305
                  ||..|.|               |::..|:..|..:|:::|:|.|:||||||..||||::
Mouse   223 GVTLPTQLPLTKY---------------EERVLKKIRRKIRNKQSAQESRKKKKEYIDGLENRMS 272

  Fly   306 V--------------LENQNKALIEELKSLKELYCQT 328
            .              ||.||.:|:|:||.|:.|..|:
Mouse   273 ACTAQNQELQRKVLHLEKQNLSLLEQLKHLQALVVQS 309

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CrebB	NP_001334685.1	None
Creb3l3	NP_001369747.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	67..144		17/47 (36%)
		bZIP_CREB3	240..300	CDD:269837	22/59 (37%)
		Basic motif. /evidence=ECO:0000255\|PROSITE-ProRule:PRU00978	241..270		14/28 (50%)
		coiled coil	242..293	CDD:269837	18/50 (36%)
		Leucine-zipper. /evidence=ECO:0000255\|PROSITE-ProRule:PRU00978	281..302		8/20 (40%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167834570
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.840